Q: Explain the process of Drug Elimination
A: Drug elimination is the removal of drug from the body.
Q: What is the ultimate goal of drug metabolism? Discuss with example.
A: Drugs are any substances when taken into the body bring out psychological and physiological changes…
Q: Explain why body fluids pH can affect drug absorption and distribution.
A: pH can be defined as the negative logarithm of hydrogen ions. Normal pH scale is between acidic to…
Q: What is the mechanism of action of the drug LIDOCAINE?
A: Lidocaine is the first local anesthetic of the amino amide-type, it was firstly synthesized by Nils…
Q: List and explain in your own words the 5 mechanisms of antimicrobial drug resistance
A: Introduction: Antimicrobials selectively destroy/prevent the formation of germs such as bacteria…
Q: Discuss the actions of sulfanilamide and trimethoprim as antimetabolite.
A: According to the question, we have to discuss the actions of sulfanilamide and trimethoprim as an…
Q: List the factors affecting the passage of drugs across cell membranes.
A: Factors affecting drugs: Physiological factors that alter the providence of medications in the body…
Q: For each of the following pharmacologic classification of antihypertensive agents, list (a) at least…
A: Medications that treats hypertension or increased levels of blood pressure are known as…
Q: Define therapeutic index and explain its importance.
A: Therapeutic Index is also known as Therapeutic Ratio. It is a quantitative measurement of the…
Q: Discuss the various categories of controlled substances, and give specific drug examples in each…
A: Controlled substances: Any type of chemical that has the potential to alter the physical and mental…
Q: Explain anti drug
A: A pathogen is any infectious agent or microorganism (virus, bacterium, protozoa, etc.) that can…
Q: How do the cytochrome P450 proteins affect drug responses?Give two examples.
A: Cytochrome P450 is an enzyme.
Q: ase give point on
A: Drugs are any substances when taken into the body bring out psychological and physiological changes…
Q: Describe the influence of protein binding on drug bioavailability
A: Protein binding is the extent to which drugs can bind to proteins in the blood or tissues. The…
Q: Explain mechanisms of drug toxicity? How various strategies are used to treat the drug toxicity and…
A: Drug toxicity can be outlined as the toxicity which occurs because of ingesting more drugs that are…
Q: Describe the development of drug resistance, and explain how it is acquired.
A: Drug resistance refers to a medication's reduced effectiveness in treating a disease or condition,…
Q: When two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the…
A: When two or more drugs are used together, there happens to be some interactions between the drugs…
Q: Describe the Mechanisms of Drug Resistance with an example.
A: Resistance is improvement of the capacity to withstand the beforehand dangerous impact of a drug by…
Q: How we can improve (potency, selectivity and decrease in toxicity ) for the development of a…
A: Antihistamines are drugs that are used to treat allergic conditions like sneezing, runny nose,…
Q: Discuss the difference between first-generation and second-generation antihistamines
A: Antihistamines is a family of drug used for the treatment of allergic reactions. Histamines are…
Q: Induction of the drug metabolizing enzymes results in: a. Increasing the drug's metabolism b.…
A: Drug metabolism is a phenomenon in which the drug undergoes an alteration in its chemical state. The…
Q: Describe the fi ve basic mechanisms of drug resistance.
A: Infection is caused by microbes penetrating and multiplying within an organism's body. Bacteria,…
Q: drug-drug interaction of triazolam and ketoconazole
A: Drug interaction is defined as change in the drug desired effect caused by concomitant…
Q: Identify the criteria the compounds must meet in order to be developed into drugs.
A: A pharmaceutical drug or medicine is a compound that is used either for the diagnosis, treatment,…
Q: what are the purpose of drug metabolism?
A: Drug metabolism is metabolic breakdown of drugs in the body with the help of specific enzymes. It is…
Q: Shown below is a logD graph of drug. Which types of the drug best represents this ?graph Chet Tle
A: The answer is neutral. LogD is a distribution coefficient used to measure the lipophilicity of…
Q: Identify the classification of drug metabolism and specific type of reaction involved in each drug…
A: Drug metabolism is a metabolic drug breakdown by living organisms often through special enzymatic…
Q: how does the ratio of cholesterol to phospholipids in a liposome affect drug encapsulation?
A: Phospholipids are a type of chemical molecule that has a hydrophilic head composed of a phosphate…
Q: Describe some Specific Drugs and Their Metabolic Targets. Give some uses.
A: Drug metabolism is a term used to describe the biotransformation of drugs in the body for easy…
Q: Define about Sulfa Drugs ?
A: Antibiotics are considered chemical compounds, which are helping to prevent bacterial infections.
Q: Give two examples of macromolecules that are chosen as drug targets. What are antiseptics? Give an…
A: Macromolecules are the molecules having large molecular mass. These are mostly polymers.
Q: What is the process that leads to drug tolerance?
A: The effect of the drug lessens with repeated exposure. Bigger doses drug is required to bring…
Q: What is the mode of action of beta lactam drugs
A: Antibiotics are drugs that are used to stop infections caused by bacteria or other microbes. They do…
Q: Describe the role of receptor sites in drug action.
A: Receptors are the macromolecule which are present in the membrane or in the cell wall, that…
Q: Why may nonspecific variables have a greater impact on psychoactive drug effects than antibacterial…
A: Introduction If a person takes a psychoactive substance, it will alter his or her body's mental…
Q: Explain how drugs may interact with nucleic acids as a drug target, and outline how a medicinal…
A: Drugs are used to treat a disease. The disease is caused when there is a deviation from the normal.…
Q: a. What is a drug target? Why is it important to identify a drug target to treat a disease?
A: A drug is a molecule which might resemble a organic molecule inside the body or an exogenous…
Q: Important drug-drug or drug-food interactions are identified and satisfactorily explained for…
A: Fluticasone is used in allergy. This drug is administered through the nose. It relieves symptoms of…
Q: Briefly discuss how we can improve pharmacodynamic properties of H1-Antihistamine drugs?
A: The study involving the biochemical reactions and effect of the drug on the body is called…
Q: What is a synergistic drug interaction? Give Example
A: There are two types of effect synergistic and antagonist drug interaction. The synergistic effect of…
Describe the Mechanisms of Drug Resistance with an example.
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Solved in 3 steps
- Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction.Enumerate the different sources of drug. Provide example for each source. Discuss the advantages and disadvantages of each source.With references added,give a detailed mechanism of action for the drug Entresto.
- What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?What are the different sources of drugs? Give an drug from each of these example of a sourcesDescribe the development of drug resistance, and explain how it is acquired.