Describe the composition of the plasma membrane. Include the general structure of different types of lipids and any asymmetry in their distribution. Include the different classes of membrane proteins and different ways in which proteins are associated with the membrane

Describe the 3 major types of proteins that can be found at the plasma membrane and give examples of each type and the function that each plays in the functioning of the cell.

Explain passive transport and active transport across the cell membrane.

Which of the following statements is true about biomembrane?     Membrane proteins and lipids are distributed symmetrically in the two leaflets of the bilayer.     Lipid-linked proteins are anchored to the bilayer by the lipid moiety that covalently attached to the protein.     Lipid molecules can diffuse laterally in each leaflet of the bilayer but they can never flip from one leaflet to another.     The fluid mosaic model describes the dynamic arrangement and interaction of proteins but not lipids in membrane.     Bilayers are formed by triacylglycerol, glycerophospholipids, and sphingolipids.

Match the following statement related to membrane transport processes to the appropriate term or terms: passive transport, facilitated transport, active transport. A transporter (or carrier) protein is necessary. (Select all that apply.) passive transport facilitated transport active transport O O

Crossing a cell membrane by simple diffusion can be distinguished from facilitated diffusion by which of the following: Select all that apply. Simple diffusion moves molecules down a concentration gradient while facilitated diffusion moves molecules up a concentration gradient Simple diffusion does not require membrane proteins; facilitated diffusion requires specific membrane proteins Simple diffusion does not require energy; facilitated diffusion requires energy Simple diffusion is not saturable; facilitated diffusion rates are limited by the number of functional membrane proteins and can be saturated

Identify basic structure of the 8 types of membrane proteins shown below Understand how primary structure (e.g., regional hydrophobicity and hydrophilicity) allows proper membrane interaction/association. Compare/contrast the degree to which proteins are attached to membranes. Which have more lateral movement? Diversity of attachment and lateral movement allows efficient function. Understand where glycosylated lipids and proteins are found and what general functions they serve. Know the role/significance of cysteine disulfide bonds. On which side of the plasma membrane do they generally occur? Why? lipid bilayer A La s *****P & de www CYTOSOL COOH NH₂ cccccce 6

The plasma membrane is composed of a variety of lipid molecules. 1. Phosphatidylethanolamine 2. Phosphatidylcholine 3. Phosphatidylinositol 4. Phosphatidylserine 5. Sphingomyelin 6. Glycolipids 7. Cholesterol. Which lipids contain sugar molecules?

Describe the general structure of all cell membranes. What are three types of lipid molecules that are present in the cell membrane? Then describe how the different types of lipid molecules can impact membrane fluidity and they can impact membrane shape.