Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Q21:

Consider the hypothetical serine protease, which shows the
specificity pockets. The S₁ pocket has a glutamic acid in the
bottom, the S₂ pocket is small and hydrophobic, and the S₁'
pocket is deep and hydrophobic. Suggest an amino acid
sequence that this protease would cleave.
Which of the sequences would this protease cleave?
Val-Phe-Arg
Arg-Phe-Val
Phe-Arg-Val
Val-Arg-Phe
Arg-Val-Phe
Phe-Val-Arg
Incorrect
ZI
R3
Il
H
ZI
H
S2
ZT
S₁
Y
"Ri
S₁
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Transcribed Image Text:Consider the hypothetical serine protease, which shows the specificity pockets. The S₁ pocket has a glutamic acid in the bottom, the S₂ pocket is small and hydrophobic, and the S₁' pocket is deep and hydrophobic. Suggest an amino acid sequence that this protease would cleave. Which of the sequences would this protease cleave? Val-Phe-Arg Arg-Phe-Val Phe-Arg-Val Val-Arg-Phe Arg-Val-Phe Phe-Val-Arg Incorrect ZI R3 Il H ZI H S2 ZT S₁ Y "Ri S₁
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