Complete the table below to determine the Non-Mendelian patterns of inheritance involved in the formation of the given phenotype of the offspring produced in a cross between a homozygous black fur rabbit and white fur rabbit.
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Complete the table below to determine the Non-Mendelian patterns of
inheritance involved in the formation of the given
produced in a cross between a homozygous black fur rabbit and white fur rabbit.
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- A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What if the couple wanted prenatal testing so that a normal fetus could be aborted?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What is the chance that this couple will have a child with two copies of the dominant mutant gene? What is the chance that the child will have normal height?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?
- In cats, the genotype AA produces tabby fur color; Aa is also a tabby, and aa is black. Another gene at a different locus is epistatic to the gene for fur color. When present in its dominant W form (WW or Ww), this gene blocks the formation of fur color and all the offspring are white; ww individuals develop normal fur color. What fur colors, and in what proportions, would you expect from the cross AaWw Aa Ww?Classical Mendelian Genetics, Incomplete Dominance, Codominance, and Multiple Alleles 1. Complete the table given below regarding the phenotype and genotype ratios in completely dominant traits. R and r represent the dominant and recessive allele, respectively. Type of Cross rrx rr RR x rr Rrx rr Rrx Rr Genotype Ratio Phenotype Ratio RR x Rr RR X RR *How would the genotype ratios be affected if the mode o inheritance in incomplete dominance? Codominance? 2. In dogs, barer trait is controlled by a dominant gene D and the silent trait by the recessive gene d. Normal tail is dependent on a dominant gene M and the screw m. Give the probable genotypes of the parents in the following crosses: Phenotype of parents Phenotypes of progeny Genotypes of parents Barker Barker Silent Silent normal screw normal normal a. silent normal x silent normal b. barker normal x silent normal 0 0 6 2 7 2 8 3 c. barker normal x silent screw 4 5 5 3 d. barker screw x silent normal 6 0 0 0 e. barker screw x…Multiple Alleles- Blood Types 1. Blood Type is controlled by 3 alleles: What are they? allele is recessive alleles are codominant, and in homozygous condition results in O blood group. 2. and 3. What are the genotypes possible for a person who has: A blood? B blood? O blood? AB blood? 4. A man with type AB blood is married to a woman also with type AB blood. Show the cross. What proportion of their children will have: A blood? B blood? O blood? AB blood? 5. A man has type B blood (genotype I"I") is married to a woman with type O (ii) blood. Show the cross. What proportion of their children will have: 1. A blood? 2. B blood? 3. O blood? 4. AB blood? 6. A woman with type A blood (genotype IAi) is married to a type B person (genotype I®i). Show the cross. What proportion of their children will have: A blood? B blood? O blood? AB blood?
- Part 2: Non-Mendelian Genetics 6. For each of the genotypes below, list all possible phenotypes. Purple Flowers are dominant white flowers are recessive and heterozygous flowers are lavender. PP- Pp- pp Brown eyes are dominant, blue eyes are recessive, and heterozygous eyes are green. BB- Bb - bb- Black fur is dominant, white fur is recessive, and heterozygous fur is grey. FF - Ff- ff - 7. A woman with type A blood has a child with a man with type AB blood. Show ALL the possible crosses the child may have.ng -Courses iblic/activ 003004/a s sment al V T-Rex Game. un in to your acc. L 1.3.4 Quiz: Predicting Genetic Outcomes Question 1 of 10 Mendel used over 28,000 pea plants in his experiment. How does this large sample size make his results more reliable? O A. He was not sure which of the plants were female and which were male. B. Most of the plants were unable to reproduce, so he needed many of them. C. He used more plants so the experiment wouldn't take as long. D. It made his actual results approach the results predicted by probability. SUBMIT E PREVIOUSTrivla Game Show _Make Your Own Tri ngston.schoology.com/common-assessment-delivery/start/4789189591?action=onresume&submissionld=463322566 Dillon WF g Aa v Done In guinea pigs, black hair (B) is dominant to white hair (b) and rough hair (R) is dominant to smooth hair (r). What are all the possible genotypes of a guinea pig that has black, rough hair? (Select all that apply.) O BBRR BBRr BBrr BBRR BbRr O bbRR O bbRr O bbrr O Black O White O Rough OSmooth O Rough O Smooth
- Cases of Incomplete Dominance 1. When a straight-haired mouse is crossed with a curly-haired mouse, the result is always wavy hair. Two wavy-haired mice cross. a. What are the genotypes of the two wavy-haired mice? b. Draw the Punnett Square of a cross between two wavy-haired mice, and show the probable genotypes of their offspring. с. What is the expected phenotype ratio of the offspring? % d. What is the expected genotype ratio of the offspring?G Describe Muller's Ratchet-Googl x nooreps.owschools.com/owsoo/studentAssignment/index?eh=310247513 Asslgnment -6. Mendelian Genetics Attempt 1 of 2 ASSIGNMENTS COURSES SECTION 7 OF 8 « < 4 5 8. 9. 10 11 12 13 14 Click an item in the list or group of pictures at the bottom of the problem and, holding the button down, drag it into correct position in the answer box. Release your mouse button when the item is place. If you change your mind, dra the item to the trashcan. Click the trashcan to clear all your answers. Make a Punnett Square for two smooth seed hybrid pea plants (Ss) Click once to select an item at the bottom of the problem. Click again to drop the item in its correct place. S SS Ss SS STTGG ttgg F1 TG tg F2 TtGg Which types of genotypes are represented in F1 and F2 in the above figure, respectively? heterozygous and heterozygous heterozygous and homozygous homozygous and heterozygous homozygous and homozygous