Complete the description of the pentose phosphate pathway by filling the correct term to each blank. The pentose phosphate pathway is a two‑stage pathway that generates ______ , which is a reductant in many biosynthetic reactions and takes part in detoxifying reactive oxygen species, and __________ , which is a nucleotide (DNA and RNA) precursor. The substrate for the pentose phosphate pathway is ___________

Identify whether the statement is correct or incorrect. In krebs cycle, the enzyme called aconitase catalyzes the conversion of fumarate to malate

The highest energy point of the serine protease reaction is the formation of the tetrahedral oxyanion intermediate on the original carbonyl carbon of the scissile peptide bond. True or False? DIPF is an irreversible inhibitor of serine proteases. True or False? The acyl-enzyme intermediate is the transition state of the reaction. True or False?  Serine proteases are classified as isomerases. True or False?

Complete the interrelated pathways by providing the neccesary metabolite, enzyme, reaction or metabolic pathway. Use abbreviations/acronyms (except for coenzyme)

Amino acid degradation and biosynthesis are related metabolic processes, but they are not identical. Indicate two ways in which they are similar and one in which they are different. Be as specific as you can.

For each step of the citric acid cycle, name the enzyme responsible for the chemical transformation that occurs and classify the enzyme type: Step 1. Step 2. Step 3. Step 4. Step 5. Step 6. Step 7. Step 8. i. oxidoreductase (oxidases, reductases, dehydrogenases) ii. transferase (transaminases, kinses) iii. hydrolase (lipases, proteases, nucleases, carbohydrases, phosphateses) iv. lyase (dehydratase, decarboxylase, deaminase, hydratase) v. isomerase (racemases, mutases) vi. ligase (synthetases, carboxylaces) Enzyme Name Enzyme Type

What is the correct choice? Apoenzyme, holoenzyme, coenzyme or prosthetic group?

You are a genetic analyst and you have a patient with inherited defects of glycolysis. Specifically, this patient has severe symptoms that stem from issues in their erythrocytes (red blood cells). You find that your patient has a deficiency in Hexokinase (HK). Given this information and keeping in mind what you learned about the steps of glycolysis, bisphosphoglycerate (BPG), and the importance of 2,3 BPG for hemoglobin oxygen binding what do you predict will be the effect of this mutation? Select all that apply. decreased 2,3BPG concentrations reduced flow of metabolites through glycolysis increased 2,3BPG concentrations increased flow of metabolites through glycolysis decreased hemoglobin oxygen affinity increased hemoglobin oxygen affinity 000000

If you can clearly visualize the chymotrypsin mechanism of action, you should be able to picture the structure of the transition state right after the enzyme attacks the first substrate. Think hard about what we have covered, and visualize that transition state accurately:

c) Some scientists debate whether it is correct to consider pyruvate as “the end of glycolysis”. Elaborate on this statement, discussing supporting and limiting facts.