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Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Compare the resting membrane potential of a neuron with the potassium and sodium equilibrium potentials. Explain how this comparison relates to the relative permeabilities of the resting plasma membrane to these two ions.
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- Describe how resting potential is achieved and what ions are involved in it and what side of the cell membrane they are on.arrow_forwardThe concentration of potassium ions inside a nerve cell membrane is higher than the concentration of sodium ions outside the mem-brane, yet the inside of the membrane (where the cation concentra-tion is higher) is negative to the outside. Explain this observation in terms of permeability properties of the membrane.arrow_forwardBased upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Helparrow_forward
- Calculate the equilibrium membrane potentials to be expected across a membrane at 37 ∘C, with a NaCl concentration of 0.50 M on the "right side" and 0.08 M on the "left side", given the following conditions. In each case, state which side is (+) and which is (−). Membrane equally permeable to both ions.arrow_forwardDescribe the events of an action potential in terms of ions and gates or channels beginning with the generation of a local potential through the re-establishment of resting membrane potential.arrow_forwardWhat kinds of changes in ion conductance may be expected in an action potential? And how do ion channels permit these changes?arrow_forward
- Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -40 mV (a, b, c, or d)? Upwards arrows means outward direction and downwards arrow means inward direction. The length of the arrow determines the magnitude.arrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of +40 mV?arrow_forwardExplain why alterations in potassium concentrations have more powerful effects on membrane resting potentials than alterations in sodium ionsarrow_forward
- Describe leak ion channels and gated ion channels. Howare they responsible for the permeability of a restingversus a stimulated plasma membrane?arrow_forwardDescribe two things that contribute to the resting membrane potentialarrow_forwardChanges in ion permeability or ion concentration can alter the resting membrane potential of a neuron. For each of the following, select whether each condition would cause hyperpolarization (H), depolarization (D), or very little change (LC) in the resting membrane potential. A. Increase in [K*]out [Select] B. Increase in [Na]out [Select] C. Increase in Na+ permeability [Select] D. Adding TTX [Select] E. Adding dinitrophenol (a metabolic poison) [ Select]arrow_forward
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