Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Choose two genes from Figure 4.6 and draw a graph to represent the change in
transcription over time.
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Transcribed Image Text:Choose two genes from Figure 4.6 and draw a graph to represent the change in transcription over time.
a)
hours: 0 2 567
DMC1
SPS1
hours: 0 2 5 6 7 9 11
DIT1
SPS100
b)
hours: 0.5 2 5 7 9 11
DMC1
SPS1
DIT1
SPS100
fold repressed
>20
fold induced
10x 3x | 3x 10x
1:1
FIGURE 4.6. Comparison of Northern blots with DNA microarray
data. a) Results from four individual Northern blots examining four different
genes and measuring mRNA production over time, as indicated. b) Results
from a series of microarrays for the same four genes of interest. Note the color
scale on the bottom of b), where bright green indicates a 20-fold repression
and bright red indicates a 20-fold induction. Black indicates no change in
transcription (i.e., the merged microarray spot would have appeared yellow).
>20
expand button
Transcribed Image Text:a) hours: 0 2 567 DMC1 SPS1 hours: 0 2 5 6 7 9 11 DIT1 SPS100 b) hours: 0.5 2 5 7 9 11 DMC1 SPS1 DIT1 SPS100 fold repressed >20 fold induced 10x 3x | 3x 10x 1:1 FIGURE 4.6. Comparison of Northern blots with DNA microarray data. a) Results from four individual Northern blots examining four different genes and measuring mRNA production over time, as indicated. b) Results from a series of microarrays for the same four genes of interest. Note the color scale on the bottom of b), where bright green indicates a 20-fold repression and bright red indicates a 20-fold induction. Black indicates no change in transcription (i.e., the merged microarray spot would have appeared yellow). >20
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