2.) The following alcohols can be made by combining a Grignard reagent and a ketone/aldehyde followed by an aqueous acidic workup. Some can be made by multiple methods. Provide the Grignard and the appropriate electrophile. a.) a.) c.) d.) d.) 3.) Draw the following mechanism. O PhMgBr + 1.) Et₂0 2.) H₂O+ 1.) Et₂0 2.) H₂O+ 1.) Et₂0 2.) H3O+ 1.) Et₂0 2.) H3O+ 1.) Et₂0 2.) H3O+ 1.) Et₂0 2.) H3O+ Ph OH racemic OH OH racemic OH OH ОН |||| reagent. alio 1.) Circle the following molecules that can be made into a Grignard herd HO Br Br CI o O CI Br = Br

a. b. d. 8. The following reagents/conditions are capable of selectively oxidizing a primary alcohol to an aldehyde a. Swern Oxidation, Jones Reagent (H₂CrO4), DIBAL-H, PCC b. Swern Oxidation, Jones Reagent (H₂CrO4), DIBAL-H c. Swen Oxidation, PCC d. Swern Oxidation, PCC, DIBAL-H H₂O+ 9. The acid-catalyzed hydrolysis of the epoxide drawn above will give a. A diol as a 50/50 mixture of enantiomers b. A diol as an enantiopure compound c. A diol as a meso compound d. No reaction 10. The reaction below is in equilibrium. Which of the following methods will help drive the reaction forward to form a near quantitative yield of products? Circle the entire answer and all answers that apply. OCH3 OCH₂ + H₂O + 2 CH₂OH Use a large excess of methanol Use a chiral reagent Distill off the water that is formed in the reaction Add a drying agent, such as sodium sulfate

Give only typing answer with explanation and conclusion

Draw a stepwise mechanism for the following reaction. The four-membered ring in the starting material and product is called a β-lactam. This functional group confers biological activity on penicillin and many related antibiotics, as is discussed in Chapter 22. (Hint: The mechanism begins with β elimination and involves only two steps.)