CH3 CH,CH2CHCH3 HN' CH,CH3 Amytal®

Q: Specify the reagent you would use in each step of the following synthesis: OH OH step 1 step 2…

A: In the above reaction, we can see that only an alkyl chain is being added in the reactant to form…

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A: This problem is based on deprotactation and protection of diols by using different type of…

Q: In the presence of an acid catalyst, acetaldehyde forms a trimer known as paraldehyde. Because it…

A: Since O is an electronegative atom with lone pair present on it  Hence it will take H+ from the acid…

Q: An α, β-unsaturated carbonyl compound can be prepared by a reaction known as a…

A: The given reaction is represented as follows:

Q: In the presence of an acid catalyst, acetaldehyde forms a trimer known as paraldehyde. Because it…

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Q: Show how (A) can be converted to tolciclate. Use 3-methyl-N-methylaniline

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Q: Addition of one mole of HCl to isoprene gives 4-chloro-2-methyl-2-butene as the major product.…

A: The reaction between isoprene and HCl is an addition reaction. The mechanism has been discussed…

Q: Indicate how the following compounds can be synthesized from cyclohexanone and any other necessary…

A: a.

Q: Amobarbital is a sedative marketed under the trade name Amytal. Propose a synthesis of amobarbital,…

A: Structure of Amobarbital is,

Q: 2,6-Dimethoxybenzoic acid was needed for a synthesis of the β-lactam antibiotic methicillin. Show…

A: The synthesis of 2,6-dimethoxybenzoic acid from 2-bromo-1,3-benzenediol has to be given.

Q: [ 20] Which sequence of reactions would yield following compound (benzophenone) as product ? ( a)…

A: The answer will be D. Please find below the reaction mechanism.

Q: Synthesize the following compound from cyclohexanol using any other organic or inorganic compounds.…

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Q: Given this retrosynthetic analysis, propose a synthesis for the antidepressant moclobemide. CI H CI…

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Q: a OH CH2CNHCH3 CH3 C d OH CHCHNHCH3 CH3 Ephedrine can be synthesized via reductive amination plus…

A: Here we have to predict necessary reactants and reagents that will give the intermediate and final…

Q: How would you prepare benzylamine (CeHsCH,NH) from each compound? In some cases, more than one step…

A: aC6H5CH2Br + HNH2à C6H5CH2NH2 + HBr   bC6H5CN  + 4H (Na + C2H5OH) à C6H5CH2NH2      c.Hoffmann’s…

Q: Propose a mechanism for this reaction

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Q: gas, Cl¬CH2CH2¬S¬CH2CH2¬Cl, was used as a poisonous chemical agentin World War I. Mustard gas is…

A: Mustered is highly alkylating agent due to the presence of two chlorine atom this chlorine and this…

Q: Cancer of the prostate is the second leading cause of cancer deaths among American males, exceeded…

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Q: Propose an efficient synthetic approach using diethyl malonate as one of the reagents for the…

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Q: ČOEt 1. EtO-Na+ OEt 3. NAOH, H,O, heat EtO 4. HCI, heat 2-Carbethoxy- 4-Butanolactone…

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Q: Propose a synthesis route to prepare 2‐phenylacetaldehyde starting from benzene:

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Q: Which of the following starting materials and reagents would be best to produce 2-hexanol? a.…

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Q: 1. Draw the structure of the organic product/s when: 1. propanal reacts with ammoniacal AgNO,…

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Q: What type of compound will be formed as the major product of the reaction below? H+ 2 CH3OH Select…

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Q: N,N-Diethyl-m-toluamide (DEET) is the active ingredient in several common insect repellents. Propose…

A: Introduction: DEET is N,N-Diethyl-m-toluamide. It is commonly used in insect repellent. It can be…

Q: -NH -OEt H2N 1. EtO Na* 2 CH,CH2OH 2. H,0 - NH -OEt H,N Barbiturates are prepared by treating a…

A: Solution:

Q: Show how to synthesize the following compounds, using appropriate carboxylic acids and…

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Q: Draw the structure(s) of the major organic product(s) obtained after workup of the following…

A: Note : N is less electronegative than O . Therefore N will donate electrons fast to carbonyl rather…

Q: What alkyl halide is needed to prepare each 1° amine by the Gabriel synthesis?

A: Introduction: Gabriel Phthalimide synthesis is the forms the primary amine from primary alkyl…

Q: Propose a synthesis for each ketone, using as one step in the sequence a Claisen condensation and…

A: The given chemical reaction is, The sodium ethoxide would abstract an alpha hydrogen from the…

Q: Identify A, B, and C, three intermediates in the synthesis of the pain reliever and anesthetic…

A: Please find below the reaction.

Q: Given this retrosynthetic analysis, propose a synthesis for the local anesthetic hexylcaine. N. + HO…

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Q: Following are structural formulas for amphetamine and methamphetamine. H NH, CH3 (a) (b) Amphetamine…

A: (a) Treatment of 1-phenylpropan-2-one with ammonia in the presence of sodium cyanoborohydride gives…

Q: Propose a synthesis for each ketone, using as one step in the sequence a Claisen condensation and…

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Q: OH CH₂CNHCH3 CH3 C d OH CHCHNHCH₂ CH3 Ephedrine can be synthesized via reductive amination plus…

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Q: Select the reagents you would use to synthesize the compound below from benzene. (More than one step…

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Q: Diphenhydramine, the antihistamine in Benadryl, can be prepared by the following two-step sequence.…

A: The structure of diphenhydramine has to be given.

Q: Salsolinol is a naturally occurring compound found in bananas, chocolate, and several foods derived…

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Q: 1. Draw the structure of the organic product/s when: 1. propanal reacts with ammoniacal AgNO,…

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Q: Propose a synthesis of the topical anesthetic cyclomethycaine from 4-hydroxybenzoic acid,…

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Q: Select the reagents you would use to synthesize the compound below from benzene. (More than one step…

A: The conversion of benzene to m-sulpho benzoic acid can be done by following three step reactions:…

Q: In the presence of a trace of acid, d@hydroxyvaleric acid forms a cyclic ester…

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Q: Alkyl Halides (X = CI, Br or I): Assume AICI, is present if needed 2 of 2 D G un acid catalyst [H+],…

A: Anwer is given as follows

Q: Q. Albuterol C₁3H21NO3 (trade names: Proventil and Ventolin) is used to prevent and treat difficulty…

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Q: Following are two possible retrosynthetic analyses for the anticholinergic drug cycri- mine. Fill in…

A: Reaction of Piperidine with epoxide ring initiates the ring opening of epoxide and the product on…

Q: Predict the products formed when cyclohexanone reacts with the following reagents. (а) CH;NH2, H*…

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Q: Following is a retrosynthetic analysis for the synthesis of the herbicide (S)-Metolachlor from…

A: The retrosynthetic method is used to predict the starting material from product structure by…

Q: 1. Predict the products or the reaction of (i) phenylacetaldehyde and (ii) acetophenone with the…

A: Organic reactions are those in which organic reactant react to form organic products.

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.