CASE: PEPTIC ULCER DISEASE Chief complain: Mr. Garcia, a 57-year-old man, was admitted yesterday after he began passing black stools. He has a two-day history of severe stomach pains and has had indigestion on and off for several months. He undergoes an endoscopy this morning and has been newly diagnosed as having a bleeding duodenal ulcer. His doctor discharge him the same day and was given with a discharge medication order. Answer the following: 4. Following a review of the discharge medication order, the following are prescribed: enalapril 5 mg twice daily, omeprazole 20 mg twice daily, and furosemide 40 mg daily. It was documented that Naproxen should be discontinued. What is the reason for this? 5. Will you recommend Mr. Garcia the use of antacids for his ulcer? 6. Considering the medical history of Mr. Garcia, below are some options that you can recommend to the doctor as a replacement for Naproxen, for his arthritis. Discuss which of the given will be suitable. • Paracetamol + Codeine • COX-2 selective inhibitors (e.g. celecoxib) • Ibuprofen

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
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Chapter25: Cardiovascular Drugs
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CASE: PEPTIC ULCER DISEASE

Chief complain: Mr. Garcia, a 57-year-old man, was admitted yesterday after he began passing black stools. He has a two-day history of severe stomach pains and has had indigestion on and off for several months. He undergoes an endoscopy this morning and has been newly diagnosed as having a bleeding duodenal ulcer. His doctor discharge him the same day and was given with a discharge medication order.

Answer the following:

4. Following a review of the discharge medication order, the following are prescribed: enalapril 5 mg twice daily,
omeprazole 20 mg twice daily, and furosemide 40 mg daily. It was documented that Naproxen should be
discontinued. What is the reason for this?

5. Will you recommend Mr. Garcia the use of antacids for his ulcer?

6. Considering the medical history of Mr. Garcia, below are some options that you can recommend to the doctor as a replacement for Naproxen, for his arthritis. Discuss which of the given will be suitable.
• Paracetamol + Codeine
• COX-2 selective inhibitors (e.g. celecoxib)
• Ibuprofen

Patient Medical History
Smoking History:
Laboratory results and other
assessment:
Current Medications:
Diagnosis:
Prescribed Medications:
PATIENT INFORMATION
mild chronic cardiac failure (CCF)
arthritis
life-long smoker
BP-115/77 mmHg (low blood pressure)
Pulse Rate- (87 bpm- mild tachycardic)
Hemoglobin- 10.3 g/dL (range 12-18 g/dL)
Platelets 162 x 10%/L (range 150-450 x 10⁹/L)
INR 1.1 (range 0.8-1.2)
Peripheral Blood Smear- Positive for microcytic anemia
No active bleeding and no signs of hypovolaemic shock
Enalapril 5 mg twice daily for 2 years
Furosemide 40 mg daily for 2 years
Naproxen 500 mg twice daily
Duodenal Ulcer
Omeprazole 20 mg twice daily
Transcribed Image Text:Patient Medical History Smoking History: Laboratory results and other assessment: Current Medications: Diagnosis: Prescribed Medications: PATIENT INFORMATION mild chronic cardiac failure (CCF) arthritis life-long smoker BP-115/77 mmHg (low blood pressure) Pulse Rate- (87 bpm- mild tachycardic) Hemoglobin- 10.3 g/dL (range 12-18 g/dL) Platelets 162 x 10%/L (range 150-450 x 10⁹/L) INR 1.1 (range 0.8-1.2) Peripheral Blood Smear- Positive for microcytic anemia No active bleeding and no signs of hypovolaemic shock Enalapril 5 mg twice daily for 2 years Furosemide 40 mg daily for 2 years Naproxen 500 mg twice daily Duodenal Ulcer Omeprazole 20 mg twice daily
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