
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Transcribed Image Text:vny can acetone sometimes be detected in the
breath of patients with type 1 diabetes?
A. Glucagon signaling is faulty,
leading to an excess of
oxaloacetate, which enables
acetyl-CoA to enter the citric acid
cycle, therefore resulting in the
production of ketone bodies
including acetone
OB. Insulin signaling is faulty, so
excess malonyl-CoA is generated,
which leads to excess acetyl-CoA
from beta oxidation
Oc. None of the other answers is
correct
OD. Insulin signaling is correct, but
excess acetyl-CoA is generated
anyway, leading to the production
of ketone bodies including
acetone
O E. Insulin signaling is faulty, fatty
acids are catabolized to acetyl-
COA despite high blood glucose,
and excess acetyl-CoA is
converted to ketone bodies,
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