Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the salt factor (S) is 1 and bioavailability fraction (F) is 0.7. Give your answer to the nearest whole number of micrograms. The equation below can be used: Loading Dose = Cp desired x Vd S x F
Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the salt factor (S) is 1 and bioavailability fraction (F) is 0.7. Give your answer to the nearest whole number of micrograms. The equation below can be used: Loading Dose = Cp desired x Vd S x F
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The
desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the
salt factor (S) is 1 and bioavailability fraction (F) is 0.7.
Give your answer to the nearest whole number of micrograms.
The equation below can be used:
Loading Dose = Cp desired x Vd
S x F
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