(c) (d) 15.7 Complete these reactions involving lithium diorganocopper (Gilman) reagents (b) D. CuLi 2 Culi Layouts Culi 2 ether ether ether ether

Predict the products, if any, of the following reactions. 20-35 (a) ascorbic ac (1) LiAlH4 -COOH (2) H3O+ (b) (1) NaCN CH₂Br (2) H3O+, heat (c) (1) SOCl2 (d) KMnO4, H₂O oct-4-yne (warm, concd.) (2) AlCl3 COOH (e) CH₂OH Na2Cr2O7, H2SO4 (f) Ph (1) BH3.THF CH3CH2-CH-COOH (2) H₁₂O+

2 (a) Allylation is a powerful way to make compounds such as 8 and 9 diastereoselectively. OH он allylation Ph or Ph Ph 8 9 (i) Allyl Grignard reagents [RCH=CHCH,MgBr] cannot be used to make 8 and 9 selectively. With the aid of a diagram explain why. (ii) Which isomer of the allyl boronate 10 would you require to synthesise 8 selectively? Draw and provide comments on the transition state of the allylation reaction of 10 with benzaldehyde to support your answer. B-O 10

What is the purpose of HCl in the iodination of vanillin. And what is the complete mechanism for this reaction, along with how do you synthesize the catalyst and electrophil I-Cl.

Draw structures 1 and 2. CI Zn(Hg) H 2 HCI 1. Compound 2 is an isomer of 1. 2. 'H-NMR 7.16 (m, 4H), 3.16 (1H), 2.84 (2H), 1.95 (2H), 1.26 (d, 3H). Create OscerSketch Answer 1 Provide the products of the first and second reaction. H3C Na/NH3/ELOH O3/(CH3)2S Create OscerSketch Answer 2

8 and 9 please

b) 4. You must use enolate anion chemistry as part of a synthesis of the following molecules. ( a) You may not use Grignard or Cuprate Chemistry in these problems but you my use any other Chem 241/2 reagent! X-~ Ph. H3C H OH Ph OH H Ph

Want solution asap....

11) For the following reaction, identify the Lewis acid and the Lewis base and draw the curved arrow mechanism. H H -N - +) NH2 lewis base lewis Aciol SHN pinb!7 (P 12) Which of the following solvents can be used with NaNH2 and why? 02H (2 (9 HOʻHO H A.

نقطتان )2 Choose the best solvent to the following (Chloroacetic acid) CICH2-C-OH Soluble in ether Not soluble in ether هذا السؤال مطلوب إرسال LAllaa Google lai e 19all 65 Jhl pe beul.okE Google Je lael d9 sall Lia sLail a pl ell la allla ala Google alai