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Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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Question
A reactive nucleotide building block obtained by the reaction (9) which occurs in the presence of a weak base diisoprpylethlamine. Write down a detailed mechanism for the reaction 9
![(Bz-)
Meo
NH.
Polystyrene
HN
Meo
-Leu-Pro-N
(DMT--)
(21)
CCl;CO2H
[10]
(22)
(23) (20)
chemical catalyst
Bz.
NH
BZNH
[9]
DMTr-O,
DMTr-O.
OCH2CH2CN,
iPr,NEt
HO
iPr2N
OCH,CH,CN](https://content.bartleby.com/qna-images/question/b5d13fda-2b80-4bb2-a883-8b12d90f3849/0e8c114d-8e3e-4707-a363-bc0e109e5155/h8r75c_thumbnail.jpeg)
Transcribed Image Text:(Bz-)
Meo
NH.
Polystyrene
HN
Meo
-Leu-Pro-N
(DMT--)
(21)
CCl;CO2H
[10]
(22)
(23) (20)
chemical catalyst
Bz.
NH
BZNH
[9]
DMTr-O,
DMTr-O.
OCH2CH2CN,
iPr,NEt
HO
iPr2N
OCH,CH,CN
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