Blood is buffered by carbonic acid and the bicarbonate ion. Normal blood plasma is 0.024 M in HCO3 and 0.0012 M H2CO3 (pK, for H2CO3 at body temperature is 6.1). a. What is the pH of blood plasma? b. If the volume of blood in a normal adult is 5.0 L, what mass of HCl can be neutralized by the buffering system in blood before the pH falls below 7.0 (which would result in death)? c. Given the volume from part (b), what mass of NaOH can be neutralized before the pH rises above 7.8?

Blood is buffered by carbonic acid and the bicarbonate ion. Normal blood plasma is 0.024 M in HCO3 and 0.0012 M H2CO3 (pK, for H2CO3 at body temperature is 6.1). a. What is the pH of blood plasma? b. If the volume of blood in a normal adult is 5.0 L, what mass of HCl can be neutralized by the buffering system in blood before the pH falls below 7.0 (which would result in death)? c. Given the volume from part (b), what mass of NaOH can be neutralized before the pH rises above 7.8?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

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Concept explainers

Acid Base Titration

An acid-base titration is the method of quantitative analysis for determining the concentration of an acid and base by exactly neutralizing it with a standard solution of base or acid having known concentration.

Question

**Buffering Systems in Blood**

Blood is buffered by carbonic acid and the bicarbonate ion. Normal blood plasma is 0.024 M in \( \text{HCO}_3^- \) and 0.0012 M \( \text{H}_2\text{CO}_3 \) (pK\(_a\) for \( \text{H}_2\text{CO}_3 \) at body temperature is 6.1).

**Questions:**

a. What is the pH of blood plasma?

b. If the volume of blood in a normal adult is 5.0 L, what mass of HCl can be neutralized by the buffering system in blood before the pH falls below 7.0 (which would result in death)?

c. Given the volume from part (b), what mass of NaOH can be neutralized before the pH rises above 7.8?

These questions explore the buffering capacity of blood, specifically focusing on its ability to neutralize acids and bases while maintaining a pH that is necessary for human life.

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Hh.129.
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