b) In a polar solvent such as water, the SN1 and E1 reactions of a tertiary alkyl halide have the same rate. c) Which is more basic and why?: OH or tert-butoxide OCCH3 (you replace the H in hydroxide with t-butyl group)
Q: SCH, (a) H3C" CH3 OCH3 (b) H3C CH3 OCH3 Br (с) OCH3 ČH3 ČH3
A:
Q: Which do you think is a stronger nucleophile in an SN2 reaction-pyridine or pyrrole? Explain. H.…
A: The complete Lewis structures of the two compounds are
Q: Which alkyl halide in attached pair reacts faster in an SN1 reaction?
A:
Q: Ph. OTs OTs NaOH NANH, ? ? NaOH ? A В C Ph. CI NaOH dilute NaOH ? D
A:
Q: Draw the major E2 elimination product formed from the following alkyl halide.
A: E2 elimination reaction involves removing of leaving group along with a proton that results in…
Q: *OCH3 Br DMSO HO
A: Charged species of alcohol(methoxide -OCH3) are strong nucleophiles. So which undergoes via SN2…
Q: How does the strength of the nucleophile affect an SN1 or SN2 mechanism?
A: Given reaction types, SN1 reaction mechanism SN2 reaction mechanism
Q: "Drawing the Product of Inversion in an SN2 Reaction Label the nucleophile and leaving group, and…
A: Nucleophile : It should contained lone pair or negative charges. leaving group : this group will…
Q: D. Is the nucleophile strong or weak? E. Is the solvent polar protic or polar aprotic? F. What type…
A: Note: polar protic solvent and weak nucleophile and secondary alkyl halide all favors a sn1…
Q: 5. Explain why the nitrogen on the molecule on the left below is more reactive as a nucleophile than…
A: Nucleophilicity depands On negative charge density.
Q: How to Form an Internal Alkyne by Two Sequential SN2 Reactions ?
A: The terminal alkynes are those alkynes in which the triple bond is present between the first and the…
Q: Br Br or
A:
Q: Which benzylic halide reacts faster in an SN1 reaction? Explain.
A: The explantion for the classification stated above is as follows :
Q: Which alkyl halide reacts the FASTEST in an SN2 mechanism?
A: SN2 mechanism:
Q: Draw the major E2 elimination products from the attached alkyl halides.
A: In E2-elimination reaction, the C=C bond is formed by the elimination of hydrogen and halogen from…
Q: Draw the product of the E2 reaction shown below. Include all lone pairs. Ignore byproducts. -:O-CH3…
A: Elimination reaction is a type of chemical reaction which is mainly used to convert saturated…
Q: d. Draw the elimination product that would form upon reaction of (4S)-1-bromo-4- methylhexane with…
A: The reactant used is (4S)-1-bromo-4-methylhexane. The reagents used are (CH3)3COH and (CH3)3COK.
Q: 3. Rank the following in order by the rate in which they could participate in an SN1 reaction (“1"…
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Q: How does changing the leaving group from I− to Br− affect the rate of an E2 reaction?
A: E2 mechanism occurs is a single step concerted reaction with one transition state. The rate at which…
Q: Explain the strength of the base usually determines whether a reaction follows the E1 or E2…
A: Elimination reaction is the reaction in which small molecule like water, ammonia are eliminated.…
Q: Circle the major product in the E1 reaction of the following alkyl halides
A:
Q: Which of the following is the most reactive in an E2 reaction?
A: E2 is bimolecular elimination reaction.
Q: Rank the following molecules in order of increasing relative rate of SN1 reaction with methanol,…
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Q: Which one favors E2 reaction? A) isopropoxide ion B) tert-butoxide ion C) ethoxide ion D)…
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Q: Which is the better retrosynthesis for the given target molecule? Explain, and provide a one-step…
A: E option is correct.
Q: For each pair, predict the stronger nucleophile in the SN2 reaction (using an alcohol asthe…
A: A stronger nucleophile is the one, which can donate lone pairs easily.
Q: What
A: A) potassium tertbutoxide is stearicall hindered reagent so Hoffman product is major.
Q: The nucleophile approaches from the opposite side of the carbon with the leaving group in which…
A: It is SN2 reaction. In SN2 reaction i.e nucleophilic substitution biomolecular, one bond is broken…
Q: In the SN1 reaction, the 2nd step is the rate determining step. The SN1 reaction yields a total…
A: Given In SN1 Reaction, the second step is the rate-determining step. The SN1 reaction yields a…
Q: 4. For the following reaction, draw a reasonable mechanism showing stereochemistry Br-Br
A: Reaction of of cyclohexene with bromine:
Q: Which of the following reactions often competes with the SN2 reaction needed to make an ylide from…
A: The correct option is (b) i.e. E2 mechanism.
Q: Rank the following E2 reactions in order of increasing rate. Ph, OTs OTs NaOH NaOH ? NaNH, A Ph.…
A: E2 reaction is bimolecular elimination reaction. Rate = kRXBase, X is the leaving group Rate is…
Q: From each pair, select the stronger nucleophile. Q.)Cl- or I- in DMSO
A: The species, that make a covalent bond by donates a pair of electrons is known as nucleophile.…
Q: nydrogen and the leaving group have to be antiperiplanar in which reaction? E2
A: There are two types of elimination reactions. First is E1 and other is E2. (Dear student,…
Q: (8) Which nucleophile in cach pair will react faster in SN2 reactions? Circle one choice in cach…
A: Nucleophile donates a pair of electrons to bond with the other atom. Molecules or ions with one or…
Q: (b) Which of the following will react most slowly with cyanide nucleophile (NC-) in an Sn1 reaction?…
A:
Q: Explain why alkylation of an a-carbon works best if the alkyl halide used in the reaction is a…
A: The alkylation reaction of an α-carbon depends on the R-X (alkyl halide) used in the reaction. The…
Q: if this react with (CH3)3CO- what is possible product and why sn1 reaction is not possible??…
A: The reaction does not follow the SN1 due to steric hindrance of tertiary butoxide so basically both…
Q: For the substitution (SN2) reaction below circle the nucleophile and draw a box around the…
A:
Q: In the given condensed formula, I understand that there will be a carbocation rearrangement due to…
A: The E1 mechanism of conversion of secondary alcohol to alkene is given in step two.
Q: For the following dehydrohalogenation (E2) reaction, draw the Zaitsev product(s), showing the…
A: E2 is a bimolecular elimination reaction. The mechanism of this reaction involves only one step. In…
Q: Rank the alkyl halides in attached group in order of increasing reactivity in an E2 reaction ?
A: E2 elimination reactions follows single step mechanism. The mechanism involves the cleavage of C-H…
Q: Determine whether the sollowing are SN1,SN2, E1, or E2 and draw the major product and if more than…
A:
Q: For SN1 Explain the order in which 1o (primary) alkyl halides reacted (fastest to slowest) and…
A: The rate of the SN1 reactions depends upon the concentration of alkyl halide only. This kind of…
Q: 1. Rank the following according to increasing reactivity (1 - least reactive, 4 - most reactive in a…
A:
Q: Azulene, an isomer of naphthalene, having fused 5 and 7 membered rings, has the following orbital…
A: Azulene: It is non-benzenoid fused ring system in which 5-membered and 7-membered ring systems are…
Q: 1. What is the nucleophile in the reaction? 2. The reaction above follows what mechanism? 3. What is…
A: It is the basic part of the reaction mechanism. Here we have to be clear about the nucleophile,…
Q: но, b) H
A:
Q: Rank the nucleophiles in each group in order of increasing nucleophilicity.a. -OH, -NH2, H2Ob. -OH,…
A: Nucleophilicity increases with increase in basicity of species. Across a period from right to left…
explain the following and show reactions that apply.
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- Consider the E1 reaction of the tertiary halide shown. Н. :Br: : ОН H :Br: + NaOH -H- product Step 1: Add curved arrow(s). Step 2: Add curved arrow(s). Select Draw Rings More Erase Select Draw Rings More Erase C H Br C H Br : Br : H : Br H H 'o:6). What is the major product of the following reactions? (A) -? coon 1). NaOH in ErOH, then H,O+ 2). 1 eqiv. NaOEt 3). 1 equiv. CH3Br 4). H₂O*, Heat COOB (Intramolecular Claison) COOE (B) CH₂ COOH (D) CH₂ (E) CH3 CH₂2 Draw the H mechanism ľ Br for the E2 reaction below. Assume base is Be
- Consider both 5-methyl-1,3-cyclopentadiene (A) and 7-methyl-1,3,5-cycloheptatriene (B). На He -Hp Ha A в Which labeled H atom is most acidic? H, is most acidic because its conjugate base is antiaromatic. H, is most acidic because its conjugate base is antiaromatic. Hj is most acidic because its conjugate base is aromatic. H, is most acidic because its conjugate base is aromatic. Which labeled H atom is least acidic? H. is least acidic because its conjugate base is antiaromatic. H, is least acidic because its conjugate base is aromatic. H, is least acidic because its conjugate base is antiaromatic. Ha is least acidic because its conjugate base is aromatic.Which of the following Alkyl halides (R-X) reacts fastest in an SN2 reaction? A) 3-bromopentane B) 1-bromo-3-methylpentane C) 2-bromo-2-methylpentane D) 2-bromopentane E) 1-bromo-2,2-dimethylpentane O A OB OC SOD OE Proctorio is sharing your screen. hp Stop sharing Hide Quiz savIdentify the reagents needed to come up with the given compounds. Pls Separate the reagents with a comma and a space. (ex. HNO3, H2SO4). For a multi-step reaction, separate the reagents with a semi-colon. (ex. HNO3, H2SO4; CH3Cl, AlCl3) There should be 9 reagents
- A set of three nucleophilic displacement reactions is shown below: Br CH3 BRCH,CHCH,CH,CH,CH3 Br CH3CHCH,CH,CH,CH3 CH3CCH,CH2CH,CH3 CH3 A B H20, CH;CH,OH SN1 reaction Which reaction (A, B, or C) proceeds the fastest? Which reaction (A, B, or C) proceeds the slowest?Which of the following statements about nucleophilic reactions are generally true ? V SN2 reactions rely on least hindered substrates. 1° are best while 3° are worst. V SN1 and E1 reactions rely on good carbocation forming substrates. Benzylic, allylic, 3° are best while 1° are worst. V E2 reactions depend primarily on strong bases like hydroxides, alkoxides, or amides. V Polar aprotic solvents like HMPA, DMF, DMSO, acetonitrile, or acetone are favoring SN2. V Polar protic, neutral or acidic solvents/environments like alcohols, water, or acidic solutions favor SN1/E1 mechanisms. SN2 and E2 reactions are stereospecific, while SN1 occurs with racemization. Elimination reactions are expected to result in Zaitsev's (more substituted) product(s), unless hinderance steers them into Hoffman's (less substituted) product(s).Rank the following E2 reactions in order of increasing rate. Ph, OTs OTs NaOH NaOH ? NaNH, A Ph. dilute NaOH NaOH E
- Ql- Arrange the following carbonium ion as more stable. Why? Me Me „Me A C Q2- Choose the substituted group that makes the following reaction faster. Why? X- CH2 H X- ососн, OR COOCH} Y= NH2 OR NO2 Q3- Which of the following compounds give the highest yield when reacting with a carbonyl compound. Why? NH 2 NH2 NH2 Me Me Me OR OR NO 2 NO2 NO2For SN1 Explain the order in which 1o (primary) alkyl halides reacted (fastest to slowest) and explain why. The 1o primary alkyl halides are: (see picture below) 1-chlorobutane 1-bromobutane 1-chloro-2butene benzylchlorideWhat is the major product of this reaction? A - because a ketone is a meta-director A - because a halide is a meta-director B - because a ketone is an ortho,para-director B - because a halide is an ortho,para-director 2. Rank the following compounds in order of increasing reactivity in a bromination reaction.(1 = slowest ... 3 = fastest)