) At the epiphyseal plate some chondrocytes undergo hypertrophy. This means they: a) increase in number. b) increase in size. c) accumulate calcium. d) bind to the ossification center.
1) At the epiphyseal plate some chondrocytes undergo hypertrophy. This means they:
a) increase in number.
b) increase in size.
c) accumulate calcium.
d) bind to the ossification center.
Chondrocytes hypertrophy is a characteristics of osteoarthritis and it dominates the growth of bone.
Growth plate is an important tissue which mediates and control the bone growth.It forms through multistep differentiation process in which differentiation, proliferation, stopping of division and hypertrophy of Chondrocytes occurs.
Hypertrophic chondrocytes are specialized cells which are the end state of Chondrocytes differentiation pathways and are important for growth of bone.
Hypertrophic Chondrocytes instruct the adjacent perichondrial cells to differentiate into osteoblasts.
Shortly after that,there is formation of primary ossification center inside the template of cartilage.
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