Assume a length of axon membrane of about 0.10 m is excited by an action potential (length excited = nerve speed x pulse duration = 50.0 m/s x 0.0020 s = 0.10 m). In the resting state, the outer surface of the axon wall is charged positively with K+ ions and the inne equal and opposite charge of negative organic ions, as shown in the figure below. Model the axon as a parallel-plate capacitor and take C = xc A/d and Q = CAV to investigate the charge as follows. Use typical values for a cylindrical axon of cell wall thickness d = 2.0 x 1 radius r = 1.6 x 10¹ μm, and cell-wall dielectric constant x = 2.9. External fluid Positive charge layer { Negative { charge layer Axon wall membrane Internal fluid Axon radius r d @ (a) Calculate the positive charge on the outside of a 0.10-m piece of axon when it is not conducting an electric pulse. (Assume an initial potential difference of 7.0 x 10-² V.) 9.03E-10 How many K+ ions are on the outside of the axon assuming an initial potential difference of 7.0 x 10-² V? 5.639E9 ✓K+ ions Is this a large charge per unit area? Hint: Calculate the charge per unit area in terms of electronic charge e per angstrom squared (A2). An atom has a cross section of about 1 A² (1 A-10-10 m). (Compare to normal atomic spacing of one atom every few Å.) O Yes

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Assume a length of axon membrane of about 0.10 m is excited by an action potential (length excited = nerve speed x pulse duration
equal and opposite charge of negative organic ions, as shown in the figure below. Model the axon as a parallel-plate capacitor and take C = K² A/d and Q
radius r = 1.6 × 10¹ μm, and cell-wall dielectric constant x = 2.9.
=
Positive
charge
layer
Negative
charge
layer
+
External fluid
Axon wall membrane
No
Axon radius = r
+
Internal fluid
+
How many sodium ions (Na+) is this?
Na+ ions
d
+
(a) Calculate the positive charge on the outside of a 0.10-m piece of axon when it is not conducting an electric pulse. (Assume an initial potential difference of 7.0 × 10-² V.)
-2
9.03E-10
C
How many K+ ions are on the outside of the axon assuming an initial potential difference of 7.0 × 10-² V?
5.639E9
K+ ions
= 50.0 m/s X 0.0020 s = 0.10 m). In the resting state, the outer surface of the axon wall is charged positively with K+ ions and the inner wall
CAV to investigate the charge as follows. Use typical values for a cylindrical axon of cell wall thickness d = 2.0 × 10-8 m
Is this a large charge per unit area? Hint: Calculate the charge per unit area in terms of electronic charge e per angstrom squared (Å2). An atom has a cross section of about 1 Ų (1 Å = 10-10 m). (Compare to normal atomic spacing of one atom every few Å.)
Yes
(b) How much positive charge must flow through the cell membrane to reach the excited state of +3.0 × 10-2 V from the resting state of -7.0 × 10-² V?
3.87E-10 X
Your response differs from the correct answer by more than 10%. Double check your calculations. C
+
(c) If it takes 2.0 ms for the Na ions to enter the axon, what is the average current in the axon wall in this process?
μA
(d) How much energy does it take to raise the potential of the inner axon wall to +3.0 × 10-2 V, starting from the resting potential of -7.0 x 10¯ V? (Assume that no energy is required to first raise the potential to 0 V from the resting potential of -7.0 x 10-² ² V.)
J
Transcribed Image Text:Assume a length of axon membrane of about 0.10 m is excited by an action potential (length excited = nerve speed x pulse duration equal and opposite charge of negative organic ions, as shown in the figure below. Model the axon as a parallel-plate capacitor and take C = K² A/d and Q radius r = 1.6 × 10¹ μm, and cell-wall dielectric constant x = 2.9. = Positive charge layer Negative charge layer + External fluid Axon wall membrane No Axon radius = r + Internal fluid + How many sodium ions (Na+) is this? Na+ ions d + (a) Calculate the positive charge on the outside of a 0.10-m piece of axon when it is not conducting an electric pulse. (Assume an initial potential difference of 7.0 × 10-² V.) -2 9.03E-10 C How many K+ ions are on the outside of the axon assuming an initial potential difference of 7.0 × 10-² V? 5.639E9 K+ ions = 50.0 m/s X 0.0020 s = 0.10 m). In the resting state, the outer surface of the axon wall is charged positively with K+ ions and the inner wall CAV to investigate the charge as follows. Use typical values for a cylindrical axon of cell wall thickness d = 2.0 × 10-8 m Is this a large charge per unit area? Hint: Calculate the charge per unit area in terms of electronic charge e per angstrom squared (Å2). An atom has a cross section of about 1 Ų (1 Å = 10-10 m). (Compare to normal atomic spacing of one atom every few Å.) Yes (b) How much positive charge must flow through the cell membrane to reach the excited state of +3.0 × 10-2 V from the resting state of -7.0 × 10-² V? 3.87E-10 X Your response differs from the correct answer by more than 10%. Double check your calculations. C + (c) If it takes 2.0 ms for the Na ions to enter the axon, what is the average current in the axon wall in this process? μA (d) How much energy does it take to raise the potential of the inner axon wall to +3.0 × 10-2 V, starting from the resting potential of -7.0 x 10¯ V? (Assume that no energy is required to first raise the potential to 0 V from the resting potential of -7.0 x 10-² ² V.) J
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