Aspirin (acetylsalicylic acid, structure below), has a pKa of 3.5. The pH at whichaspirin is most soluble is water isOCOCH3COOHpH = 0pH >> 3.5pH = 3.5pH << 3.5

Therefore, aspirin is most soluble in water when the pH is significantly higher than its pKa (pH…

Answered: Aspirin (acetylsalicylic acid,…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Aspirin (acetylsalicylic acid, structure below), has a pKa of 3.5. The pH at which aspirin is most soluble is water is OCOCH3 COOH pH = 0 pH >> 3.5 pH = 3.5 pH << 3.5