Aside from the specified main starting material, only the following compounds can be used as sources of the carbon backbone for the target compound: acetaldehyde ethanol propanoic acid acetic acid ethyl bromoacetate propan-1-ol benzene (2E,4E)-hexa-2,4-diene propan-2-ol buta-1,3-diene methanol propan-2-one (acetone) (chloromethyl)benzene (benzyl chloride) 5-methyloxolan-2-one sodium cyanide 1-(chloromethyl)-4-methylbenzene phenylacetaldehyde sodium methoxide diethyl propanedioate (diethyl malonate) piperidine sodium ethoxide - There are no restrictions with regards to the use of other reagents such as catalysts, solvents, redox agents, protection/deprotection agents, etc. as long as they will not be used as sources of carbon for the skeleton of the target compound. 1. Design a retrosynthetic map and from it, propose a multi-step synthetic approach for the preparation of the target compound from the specified starting material. 2. Write both the retrosynthesis and synthesis plan
Aside from the specified main starting material, only the following compounds can be used as sources of the carbon backbone for the target compound:
acetaldehyde |
ethanol |
propanoic acid |
acetic acid |
ethyl bromoacetate |
propan-1-ol |
benzene |
(2E,4E)-hexa-2,4-diene |
propan-2-ol |
buta-1,3-diene |
methanol |
propan-2-one (acetone) |
(chloromethyl)benzene (benzyl chloride) |
5-methyloxolan-2-one |
sodium cyanide |
1-(chloromethyl)-4-methylbenzene |
phenylacetaldehyde |
sodium methoxide |
diethyl propanedioate (diethyl malonate) |
piperidine |
sodium ethoxide |
- There are no restrictions with regards to the use of other reagents such as catalysts, solvents, redox agents, protection/deprotection agents, etc. as long as they will not be used as sources of carbon for the skeleton of the target compound.
1. Design a retrosynthetic map and from it, propose a multi-step synthetic approach for the preparation of the target compound from the specified starting material.
2. Write both the retrosynthesis and synthesis plan
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