Answer the following questions related to the separation of a mixture containing the following molecules: Compound 1 Structure OH 2 3 4 OH OH (a) What is the DOMINANT intermolecular force that will attract each compound to bind to silica gel? Compound 1 Intermolecular Force 2 3 4 H-Bonding H-Bonding Dipole-Dipole H-Bonding (b) The following compounds were separated by silica gel chromatography. Each compound was collected and placed in flasks labeled A, B, C and D respectively, in order of their elution from the column (i.e., the compound in flask A eluted first, B eluted second, C eluted third, and D eluted last). Indicate which compound 1-4 you would expect in each flask. Flask A Compound 3 B 2 C 1 D 4

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Please explain why for part b) the compounds are eluted in that order. Thank you!

Answer the following questions related to the separation of a mixture containing the following
molecules:
Compound
1
Structure
OH
2
3
4
OH
OH
(a) What is the DOMINANT intermolecular force that will attract each compound to bind to silica gel?
Compound
1
Intermolecular Force
2
3
4
H-Bonding
H-Bonding
Dipole-Dipole
H-Bonding
(b) The following compounds were separated by silica gel chromatography. Each compound was
collected and placed in flasks labeled A, B, C and D respectively, in order of their elution from the
column (i.e., the compound in flask A eluted first, B eluted second, C eluted third, and D eluted last).
Indicate which compound 1-4 you would expect in each flask.
Flask
A
Compound
3
B
2
C
1
D
4
Transcribed Image Text:Answer the following questions related to the separation of a mixture containing the following molecules: Compound 1 Structure OH 2 3 4 OH OH (a) What is the DOMINANT intermolecular force that will attract each compound to bind to silica gel? Compound 1 Intermolecular Force 2 3 4 H-Bonding H-Bonding Dipole-Dipole H-Bonding (b) The following compounds were separated by silica gel chromatography. Each compound was collected and placed in flasks labeled A, B, C and D respectively, in order of their elution from the column (i.e., the compound in flask A eluted first, B eluted second, C eluted third, and D eluted last). Indicate which compound 1-4 you would expect in each flask. Flask A Compound 3 B 2 C 1 D 4
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