Answer all the following questions. 1. The formulation of oral suspensions requires the following considerations: Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations. 2. The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers. 2a. How the cracking is occurring in the emulsions? 2b. If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena. 3. Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examples.
Answer all the following questions. 1. The formulation of oral suspensions requires the following considerations: Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations. 2. The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers. 2a. How the cracking is occurring in the emulsions? 2b. If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena. 3. Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examples.
Chapter23: Pediatric Intravenous Medications
Section: Chapter Questions
Problem 38SST
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Transcribed Image Text:Answer all the following questions.
1. The formulation of oral suspensions requires the following
considerations:
Both the physical properties of the API and the excipients are
essential to ensure that the formulation is physically stable and
suitable for administration to patients. Discuss the general
formulation considerations.
2. The instability of emulsions may be either reversible or
irreversible. Cracking indicates the extensive coalescence of the
internal phase, consequently, leads to the separation of the
emulsion into two distinct layers.
2a. How the cracking is occurring in the emulsions?
2b. If an emulsion has cracked will it be recovered. If yes/no
discuss the phenomena.
3. Discuss the lyophilization and appraise its importance in the
pharmaceutical industry with suitable examples.
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