an intravenous infusion of 200 mg of an antibiotic was given for 30 minutes. After stopping the infusion, two plasma concentrations has been taken. The concentration one hour after the end of the infusion was 8 microgg/ml, while it was 3microg/ml nine hours after the end of the infusion. Predict the approximate plasma concentration 12 hours after the dose was started. O a. 4.6 microg/ml O b. Not enough information to calculate the answer O c. 0.6 microg/ml O d. 1.15 microg/ml O e. 2.3 microg/ml Clear my choice

Order: Diltiazem HCI 125 mg in 100 mL D5W to infuse at 20 mg/hr. Available: only Usual Dosage: See package insert. DISCARD UNUSED PORTION. Non-latex. Store under refrigeration 2-8°C (36-46°F). Date removed from refrigeration NDC 10019-510-79 Diltiazem HCI Injection Date to be discarded 25 mg/5 mL (5 mg/mL) Baxter Healthcare Corporation FOR DIRECTIV BOLUS INJECTION Deerfield, IL 60015 USA 462-463-01 Determine the following: a. How many milliliters will you add to the IV? (Enter numeric value only.) mL (01)00310019510798 b. Determine the rate in mL/hr. (Consider the medication in the volume.) mL/hr

Mrs B, aged 43 years, weight 56 kg, requires a loading dose of drug B.  The target plasma concentration is 18.9 mg/ L, volume of distribution is 0.5 L/ kg, the salt factor is 0.9 and bioavailability fraction is 1. What is the intravenous loading dose (LD) of Drug B in milligrams (mg)? units - mg LD = Cp desired x Vd                         S x F   Where Cp desired is the target plasma concentration; Vd is the volume of distribution; S is the salt factor and F is the bioavailability fraction

Your patient’s recent PTT is 40. According to protocol, you need to increase the Heparin drip by 4 units/kg/hr and administer 27 units/kg IV bolus. You will recheck the PTT in 6 hours. The patient is currently receiving a Heparin drip at 18 units/kg/hr from a bag that reads 15,000 units/150 mL. The patient weighs 72 kg. How many units will the patient receive as a bolus, and how many units per kilogram per hour will the patient receive based on the new PTT result?

Erythromycin has been prescribed to a patient at your paediatric unit for the treatment of an upper respiratory tract infection. The physician’s order reads, “Give erythromycin 500 mg po BID.” Your patient weighs 24 kg.Use the drug label below to determine the safe single dosage range for your patient in mg.   Indicate the quantity and unit of measure for the minimum and maximum doses where specified. Minimum Quantity: Unit       Maximum Quantity: Unit:

Next, a 10 mg/kg sample of ibuprofen was administered orally to a laboratory rat. A blood sample was drawn after one hour and gave a peak area of 80.2.  Calculate the amount of ibuprofen in the rat’s blood after one hour.

A 16 year old boy has been prescribed the cytotoxic medication fludarabine 10mg film coated tablets at a dose of 30mg/m2 for ten days. The patient weighs 60 kg and is 1.60 m tall. Bodysurfacearea(m2)=weight(kg)xheight(cm)3600 How many 10 mg capsules are required to provide the 10 day course of treatment? units = capsules

You need to give aciclovir as an infusion at a dose of 5 mg/kg every 8 hours. The patient weighs 76 kg and aciclovir is available as 250 mg vials. How many vials do you need for each dose?

The regimen for a drug is as follows: 5mcg/kg q week x 2, then 7mcg/kg q 2 weeks. Calculate the dose in mcg that a 143 lbs. patient receives in a month.

It is 1245 and your patient has 270 mL of D5NS remaining for infusion. If the IV is running at 45 gtt/min with a drop factor of 10 gtt/mL, when do you expect the IV to be complete?Enter your answer in military time.