An allosteric enzyme that follows the concerted mechanism (MWC model) has a T/R ratio of 300 in the absence of substrate. Suppose that a mutation reversed the ratio. Note that R is the highly active form of the enzyme and T is the less active form of the enzyme. Select all of the effects this mutation will have on the relationship between the rate of the reaction (V) and substrate concentration ([S]). The enzyme would mostly be in the T form. The plot of V versus [S] would be shaped like an S, sigmoid. The enzyme would likely follow Michaelis-Menten kinetics. The plot of V versus [S] would be shaped like a hyperbola. The enzyme would be more active. Incorrect

K.R. is a 46-year-old man admitted to the emergency department with unremitting chest discomfort. The pain started while he was shoveling snow from his walkway. He had experienced chest discomfort with activity previously, but the pain had subsided with rest and he sought no medical help. This time the pain did not subside and became increasingly severe, radiating to his left arm and lower jaw. In the emergency department, an ECG and cardiac enzymes were obtained. The cardiac monitor showed sinus tachycardia with occasional premature ventricular complexes. After receiving results of his ECG and cardiac enzymes, the physician diagnoses K.R. with a myocardial infarction (MI).   What electrocardiographic (ECG) changes would indicate that K.R. is experiencing a MI? (List 3 ECG changes that would indicate MI.)   What changes in “cardiac enzymes” would be consistent with a diagnosis of MI? (List and describe 3 cardiac enzyme changes consistent with MI.)   What is the most common…

Mr.Johnsons is 6'3 tall, when you record an EKG, you must record his hieght inches. How many inches tall is Mr.Johnson?

Pathophysiology of cardiogenic shock