An allele causes homozygous individuals to die before birth. The allele is continuously being generated in the population by loss of function mutations within a gene that is important for mitosis and meiosis. Heterozygotes for the allele experience a reduction in fitness because 5% of heterozygotes are sterile. The remaining 95% of heterozygotes and all homozygotes for the wild-type allele are fertile and viable. The frequency of the allele amongst individuals at birth is 1/5000. A. What is the rate of mutation that creates this allele? B. What is the average fitness of individuals in the population? C. What is the average fitness of individuals from a mating between first cousins?

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