Activity Immediate Duration in weeks Predecessors A 3 ---- B 2 --- - C A 1 D A,B 3 E C 3 F C.D 2
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- Employee’s human capital is measured in terms of his/her age, education, tenure, and rank. Number of years an employee worked in the same organization measures the amount of firm-specific human capital that employee possesses. Data of 413 employees’ tenure was analyzed to predict interim leadership role importance in a study reported in Journal of Advanced Management Research (Vol. 9, 2012). The following table shows the data of these employees tenure in the organization: Tenure (in years) 0-1 1-6 6-11 11-20 20-21 No. of employees 48 109 58 75 123 Calculate mean tenure of these 413 employees.Benign prostatic hyperplasia is a noncancerous enlargement of the prostate gland that adversely affects the quality of life of millions of men. A study of a minimally invasive procedure for the treatment for this condition looked at pretreatment quality of life (QOL_BASE) and quality of life after three months on treatment (QOL_3MO). The data is shown on the following table: Participant QOL_BASE QOL__3MO 1 2 1 2 4 1 3 3 1 4 4 3 5 5 2 6 6 2 7 4 2 8 4 5 9 3 3 10 3 1 Calculate differences in quality of life scores (delta) for each participant.please help me out. show full working out for better understanding Hereditary hemochromatosis (HH) is a recessively inherited genetic disorder resulting from mutations in the HFE gene. There are several possible mutations of different degrees of importance but the disease expresses itself only when at least 2 arepresent in any one individual. A blood analysis was performed on 3,000 blood samples from newborn babies of Caucasian descent in the state of Michigan, USA. The results showed that 163 of those sampled carried two mutations in the HFE gene. a. What is the proportion in the sample that carry the two mutations of the HFE gene? b. Calculate the 95% confidence interval for the proportion of this population that carries two mutations in the HFE Check the data for the necessary conditions and show full working. c. Interpret your interval in context d. If the researcher wanted to halve (x ½) the margin of error in the confidence interval found, what sample size would be required…
- Omega-3, finis Exercises 21 and 23 describe an experi-ment investigating the effectiveness of omega-3 fats in treating bipolar disorder. Suppose some of the 30 sub-jects were very active people who walked a lot or got vig-orous exercise several times a week, while others tended to be more sedentary, working office jobs and watchinga lot of TV. Why might researchers choose to block thesubjects by activity level before randomly assigning themto the omega-3 and placebo groups?PTC is a substance that has a strong bitter taste for some people and is tasteless for others. The ability to taste PTC is inherited and depends on a single gene that codes for a taste receptor on the tongue. Interestingly, although the PTC molecule is not found in nature, the ability to taste it correlates strongly with the ability to taste other naturally occurring bitter substances, many of which are toxins. About 75%75% of Italians can taste PTC. You want to estimate the proportion of Americans with at least one Italian grandparent who can taste PTC. (a) Starting with the 75%75% estimate for Italians, how large a sample must you collect in order to estimate the proportion of PTC tasters within ±0.1±0.1 with 90%90% confidence? (Enter your answer as a whole number.) n=The recessive mutation bg (beige) in mice results in a decrease in the activity of natural killer cells in homozygous mutant mice. You test the hypothesis that this cell type plays an important role in rejection of tumor cells (derived from a tumor induced in an isogenic animal) by injecting animals with genotypes bg/bg or bg/+ with 106 cells and measuring the time required for the development of a palpable tumor in each animal. You obtain the following data: Time to tumor development (days) Genotype 28, 51, 47, 80 14, 35, 17, 37, 16 3. What is the most appropriate statistical approach to test the hypothesis? a. t-test for paired samples b. t-test for unpaired samples C. ANOVA d. Mann-Whitney U test e. Kruskal-Wallis test 4. Is there a significant difference in tumor latency between the two groups? bg/+ bg/bg
- PTC is a substance that has a strong bitter taste for some people and is tasteless for others. The ability to taste PTC is inherited and depends on a single gene that codes for a taste receptor on the tongue. Interestingly, although the PTC molecule is not found in nature, the ability to taste it correlates strongly with the ability to taste other naturally occurring bitter substances, many of which are toxins. About 75% of Italians can taste PTC. You want to estimate the proportion of Americans with at least one Italian grandparent who can taste PTC. Estimate the sample size required if you made no assumptions about the value of the proportion who could taste PTC. Give your answer rounded up to the nearest whole number. n = 68 IncorrectCalcium is the most abundant mineral in the human body and has several important functions. Most of the body calcium is stored in the bones and teeth, where it functions to support their structure. Recommendations for calcium are provided in Dietary Reference Intakes, developed by the Institute of Medicine of the National Academy of Sciences. The recommended adequate intake (RAI) for calcium for adults (ages 19-50) is 1000 mg per day. A random sample of 18 adults with incomes below the poverty level gave the following calcium intakes:886 633 943 847 934 8411193 820 774 834 1050 10581192 975 1313 872 1079 809Assume the population standard deviation for daily calcium intake for adults with incomes below the poverty level is 188mg.At the 0.05 level of significance, does the data provided above provide evidence to suggest that the mean calcium intake of all adults with incomes below the poverty level is less than the RAI pf 1000mg per day? Step 1: Define the parameter & setup the…A study was conducted that investigated the gene ACTN3, which encodes a protein that functions in fast-twitch muscle fibres. People can be classified according to which genotype of this gene they have, RR, RX or XX. The study included a sample of elite sprinters and a sample of endurance athletes. The researchers are investigating whether there is an association between the genotype classification and the type of athlete (sprinters or endurance). Observed counts XX RX RR Total Endurance 55 49 30 134 Sprinters 49 95 50 194 Total 104 144 80 328 What degrees of freedom should be used for this test? Explain in one or two sentences how you calculated your answer.
- A study was conducted that investigated the gene ACTN3, which encodes a protein that functions in fast-twitch muscle fibres. People can be classified according to which genotype of this gene they have, RR, RX or XX. The study included a sample of elite sprinters and a sample of endurance athletes. The researchers are investigating whether there is an association between the genotype classification and the type of athlete (sprinters or endurance). Observed counts XX RX RR Total Endurance 55 49 30 134 Sprinters 49 95 50 194 Total 104 144 80 328 The observed test statistic was 9.38 (2dp) and the associated p-value was 0.009192 (6dp). Make a decision and conclusion for this hypothesis test in context. Use a significance level of 1% (α = 0.01).Neutropenia. Neutropenia is an abnormally low number of neutrophils (a type of white blood cell) in the blood. Chemotherapy often reduces the number of neutrophils to a level that makes patients susceptible to fever and infections. G. Bucaneve et al. published a study of such cancer patients in the paper “Levofloxacin to Prevent Bacterial Infection in Patients With Cancer and Neutropenia” (New England Journal of Medicine, Vol. 353, No. 10, pp. 977–987). For the study, 375 patients were randomly assigned to receive a daily dose of levofloxacin, and 363 were given placebo. In the group receiving levofloxacin, fever was present in 243 patients for the duration of neutropenia, whereas fever was experienced by 308 patients in the placebo group. a. At the 1% significance level, do the data provide sufficient evidence to conclude that levofloxacin is effective in reducing the occurrence of fever in such patients? b. Find a 98% confidence level for the difference in the proportions of such…A mutation in Gene A is thought to be associated with a disease. The mutation in Gene A is found in 5% of the population. 2% of the whole population is diagnosed with disease B at some point in their life time. 1% of the population both has the mutation and also gets diagnosed with the disease in their life time. Is the provided data adequate to test the independency of mutation in Gene A and occurrence of Disease B? If it is not, what other information or data is needed to test the independency? What is the probability of Disease B, among the individuals with the mutation in Gene A? What is the probability of having the mutation in Gene A among the individuals with Disease B? If an individual has the mutated Gene A, what is their Relative Risk of developing the disease?