a. Propose a plausible mechanism for the following Heck reaction TBSO Pd(PPH3)4 K2CO3 H. OTBS 2.

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a. Propose a plausible mechanism for the following Heck reaction
TBSO
Pd(PPH3)4
K2CO3
H.
OTBS
2.
Transcribed Image Text:a. Propose a plausible mechanism for the following Heck reaction TBSO Pd(PPH3)4 K2CO3 H. OTBS 2.
b. The product of the reaction above is not the only one that could possibly form. In
fact, if you change up the migratory insertion step, you could make three more
isomeric structures. What do they look like? What is your guess for why they
aren't actually observed? (Assume the reaction yields only one diastereomer
regardless of which mechanistic path is followed.)
Transcribed Image Text:b. The product of the reaction above is not the only one that could possibly form. In fact, if you change up the migratory insertion step, you could make three more isomeric structures. What do they look like? What is your guess for why they aren't actually observed? (Assume the reaction yields only one diastereomer regardless of which mechanistic path is followed.)
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