a) With the help of a schematic diagram describe the synthesis of the tripeptide Phe-Leu- Met using solid phase peptide synthesis. Ensure you include the reagents used. b) Consider the reaction scheme below: i) Base OH N=c=N Intermediate, I HN- Intermediate, I (from part i) + Product, (P) + NH `NH2 by-product Draw the structure of the intermediate (I), and the product (P).

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a) With the help of a schematic diagram describe the synthesis of the tripeptide Phe-Leu-
Met using solid phase peptide synthesis. Ensure you include the reagents used.
b) Consider the reaction scheme below:
i)
Base
HO
+
N=C=N
Intermediate, I
HN
Intermediate, I
(from part i)
+
Product, (P) +
NH
*NH2
by-product
Draw the structure of the intermediate (I), and the product (P).
ZI
Transcribed Image Text:a) With the help of a schematic diagram describe the synthesis of the tripeptide Phe-Leu- Met using solid phase peptide synthesis. Ensure you include the reagents used. b) Consider the reaction scheme below: i) Base HO + N=C=N Intermediate, I HN Intermediate, I (from part i) + Product, (P) + NH *NH2 by-product Draw the structure of the intermediate (I), and the product (P). ZI
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