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A well known non steroidal anti inflammation drug NSAID exists in two sterochemical forms. Only one is biologically active. Below is the structure of the biological active form. Identify the chiral center and determine if it is the R- or S- stereoisomer.

A well known non steroidal anti inflammation drug NSAID exists in two sterochemical forms. Only one is biologically active. Below is the structure of the biological active form. Identify the chiral center and determine if it is the R- or S- stereoisomer.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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A well known non steroidal anti inflammation drug NSAID exists in two sterochemical forms. Only one is biologically active. Below is the structure of the biological active form. Identify the chiral center and determine if it is the R- or S- stereoisomer.
The image depicts the chemical structure of Ibuprofen, a commonly used nonsteroidal anti-inflammatory drug (NSAID). The molecular structure includes the following elements: - A benzene ring, which is a six-carbon ring with alternating double bonds. - Attached to the benzene ring is a propyl group (-CH2-CH2-CH3) extending to the left of the structure. - To the right of the benzene ring, the structure features a chiral center, denoted by the wedged (solid triangle) bond leading to a hydrogen atom (H) and a dashed (dashed triangle) bond leading to a methyl group (CH3). - Further to the right is a carboxylic acid group (-COOH), consisting of a carbon double-bonded to an oxygen atom (C=O) and single-bonded to a hydroxyl group (OH). This diagram is important for understanding the spatial arrangement of atoms in Ibuprofen, which influences its biological activity and its interaction with the body.
Transcribed Image Text:The image depicts the chemical structure of Ibuprofen, a commonly used nonsteroidal anti-inflammatory drug (NSAID). The molecular structure includes the following elements: - A benzene ring, which is a six-carbon ring with alternating double bonds. - Attached to the benzene ring is a propyl group (-CH2-CH2-CH3) extending to the left of the structure. - To the right of the benzene ring, the structure features a chiral center, denoted by the wedged (solid triangle) bond leading to a hydrogen atom (H) and a dashed (dashed triangle) bond leading to a methyl group (CH3). - Further to the right is a carboxylic acid group (-COOH), consisting of a carbon double-bonded to an oxygen atom (C=O) and single-bonded to a hydroxyl group (OH). This diagram is important for understanding the spatial arrangement of atoms in Ibuprofen, which influences its biological activity and its interaction with the body.
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