Phlebotomy Essentials
Phlebotomy Essentials
6th Edition
ISBN: 9781451194524
Author: Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher: JONES+BARTLETT PUBLISHERS, INC.
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Help me .
2.
Time
(h)
O246
0
6
8
12
24
A patient was given a 50 mg IV bolus dose of a drug and periodic urine samples
were collected. The observations are as follows:
Urine
volume
Collected
(ml)
120
180
89
340
178
950
Urine Time Mid-Point
Conc interval of Time
Interval
(h)
(µg/ml)
(h)
133
50
63
10
18
2
Amt
Excreted
in Time
Inteval
(mg)
Excretion Cumulative
Rate
(mg/h)
Amount
Excreted
(mg)
(a) Using "excretion rate" method and "amount to be excreted" method, estimate k,
ku, and fe of the drug.
Amount
Remaining
to be
Excreted
(mg)
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Transcribed Image Text:2. Time (h) O246 0 6 8 12 24 A patient was given a 50 mg IV bolus dose of a drug and periodic urine samples were collected. The observations are as follows: Urine volume Collected (ml) 120 180 89 340 178 950 Urine Time Mid-Point Conc interval of Time Interval (h) (µg/ml) (h) 133 50 63 10 18 2 Amt Excreted in Time Inteval (mg) Excretion Cumulative Rate (mg/h) Amount Excreted (mg) (a) Using "excretion rate" method and "amount to be excreted" method, estimate k, ku, and fe of the drug. Amount Remaining to be Excreted (mg)
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