A species of antelope has 20 chromosomes per set. The species isdivided by a mountain range into two separate populations, whichwe will call the eastern and western population. In a comparison ofthe karyotypes of these two populations, it was discovered that themembers of the eastern population are homozygous for a largeinversion within chromosome 14. How would this inversion affectthe interbreeding between the two populations? Could such aninversion play an important role in speciation?

An organism described as 2n=4 has the chromosomes below with genes indicated by letters and centromeres indicated by periods. Select the BEST description of the chromosome aberration present in this organism. HJM.NPQ HJM.NPQ S.TVXZ S.TVXXVZ Select one: 0 a. Paracentric Inversion O b. Reverse Tandem Duplication Oc. Robertsonian Translocation Od. Terminal Deletion e. Tandem Duplication Of. Nonreciprocal Translocation g. Interstitial Deletion Oh. Pericentric Inversion Homobrachial Displaced Duplication Oj. Heterobrachial Displaced Duplication Ok. Reciprocal Translocation

A researcher is interested in a gene found on human chromosome21. Describe the expected results of a FISH experiment using aprobe that is complementary to this gene. How many spots wouldyou see if the probe was used on a sample from an individual with46 chromosomes versus an individual with Down syndrome?

A researcher sequences the whole exome of a patientsuffering from Usher syndrome, a rare autosomal recessive condition that is nonetheless the leading causefor simultaneous deafness and blindness. The exomesequence does not show homozygosity for any polymorphisms different from the human RefSeq.a. How could the researcher examine the data alreadygathered to try to find the disease gene, assumingthe sequence is accurate?b. If the attempt described in part (a) was unsuccessful, the researcher might contemplate sequencingthe patient’s whole genome. What are the potentialpitfalls of this strategy?

Part A You start your experiments with the eyeless mutation on chromosome IV. You cross the reciprocal translocation strain to the eyeless pure line to generate F, flies that are both translocation heterozygotes and Ee heterozygotes. You decide to testcross F, males and females in two separate experiments to take advantage of the fact that crossing over does not occur in male Drosophila. F, males x pure eyeless females (Note: There is no crossing over F, females x pure eyeless males (Note: Crossing over in the F, males.) Cross may occur in the F, females.) 4 eyeless, fully fertile 4 wild-type, semi-sterile 4 eyeless, semi-sterile 4 wild-type, fully fertile 4 eyeless, fully fertile 4 wild-type, semi-sterile 4 eyeless, semi-sterile 4 wild-type, fully fertile F, Progeny What can you conclude from these results? Select the two correct statements. > View Available Hint(s) O The F2 progeny in both experiments contain recombinants. O The F2 progeny contain recombinants only when F, females…

When DNA sequence from a diploid individaul is of a 1,000 nucleotide region. FInd the # of pairwaise differences you can expect between the 2 of these alleles (maternal and paternal)