A significant structural feature in the digestive system is the presence of tight junctions located near the exposed sur- faces of cells lining the digestive tract. Why are these junc- tions so important?
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A significant structural feature in the
presence of tight junctions located near the exposed sur-
faces of cells lining the digestive tract. Why are these junc-
tions so important?
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- A significant structural feature in the digestive system is the presence of tight junctions near the exposed surfaces of cells lining the digestive Why are these junctions so important?Why would the amount of protein E bound to immobilized heparin fall in the presence of soluble heparin?a) (i) Give THREE (3) amino acids that most likely can be located in the part of the trans- membrane protein that lies within the cell membrane. Explain why. (ii)Give THREE (3) amino acids that most likely can be located in the part of the transmembrane protein that lies outside the cell membrane. Explain why.
- Define reninAccording to the “Hawaiian Punch” principle, different compartments of the secretory and endocytic pathways are topologically equivalent to each other and to the extracellular space. Explain how vesicular transport generates this topological equivalence. These compartments are topologically equivalent because molecules can move between them without having to move out of the cell. Transport vesicles cause this “topological equivalence” because they are responsible for the actual movement of the molecules mentioned above. They break off from one compartment, carrying the necessary molecules, and then fuse to its targeted compartment; thus, making the compartments topologically equivalent. During mitosis in mammalian cells, the nuclear envelope breaks down into vesicles. Are the topological properties of the cell altered by this event? Justify your answer.Ribosomes in the cytoplasm (cytosol) capture mRNA that can be translated into an enzyme (in this case a protease) to the lysosome. a) Describe what happens from the time the enzyme (protease) begins to form in the cytoplasm until it end up in the lysosome and explain how the enzyme is transported to the lysosome, Explain in terms of the clathrin and thethering proteins
- What four components are required for the translocation of proteins across the endoplasmic reticulum membrane?What is a dynamic, complexmeshwork of proteins and polysaccharides that contributesto the structure and function of a tissue (see Table 20-2). The major classes of ECM molecules are proteoglycans, colla-gens, and multi-adhesive matrix proteins, such as fibronectin and laminin.Many people who are lactose intolerant can eat yogurt, which is prepared from milk curdled by bacteria, without any digestive problems. Give a reason why this is possible. (Hint: Read the label on each of several yogurt containers. Do the ingredients make a difference?)
- Which of the following transporters is responsible for transporting galactose across the luminal side of the epithelial membrane of the small intestine?Polypeptides which are normally synthesized in the endoplasmic reticulum are about20 amino acids longer when they are synthesized by ribosomes not attached to the endoplasmicreticulum, What is the significance of this increase in length?Define The domain structure of cytoplasmic dynein.