A patient had shown rapid onset of hypertension and hyperglycaemia. In addition, they were showing initial signs of hyperpigmentation i.e. abdominal striae and they were also complaining of a persistent cough and difficulty in sleeping. The patient was subsequently referred for dexamethasone suppression tests (DEX). The results of these tests and additional further blood tests are shown below. Variable Urea (mm) Creatinine (mm) Cortisol (nM) (after a low dose DEX) Cortisol (nM) (after a high dose DEX) ACTH (PM) (after a high dose DEX) K+ (mm) Result 6.2 79 750 747 152 2.35 Reference Range 2.5-7.0 60-120 138-690 138 - 690 <26 3.5-5.0 Based on the patient presentation and the test results in the table, state what is the most probable diagnosis, and also the most common specific cause underlying this diagnosis. (20 words)

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Answer concisely the question in the photo (within 20 words)
A patient had shown rapid onset of hypertension and hyperglycaemia. In addition, they were showing initial signs of
hyperpigmentation i.e. abdominal striae and they were also complaining of a persistent cough and difficulty in
sleeping. The patient was subsequently referred for dexamethasone suppression tests (DEX).
The results of these tests and additional further blood tests are shown below.
Variable
Urea (mm)
Creatinine (mm)
Cortisol (nM)
(after a low dose DEX)
Cortisol (nM)
(after a high dose DEX)
ACTH (PM)
(after a high dose DEX)
K+ (mm)
Result
6.2
79
750
747
152
2.35
Reference Range
2.5-7.0
60-120
138-690
138 - 690
<26
3.5-5.0
Based on the patient presentation and the test results in the table, state what is the most probable diagnosis,
and also the most common specific cause underlying this diagnosis. (20 words)
Transcribed Image Text:A patient had shown rapid onset of hypertension and hyperglycaemia. In addition, they were showing initial signs of hyperpigmentation i.e. abdominal striae and they were also complaining of a persistent cough and difficulty in sleeping. The patient was subsequently referred for dexamethasone suppression tests (DEX). The results of these tests and additional further blood tests are shown below. Variable Urea (mm) Creatinine (mm) Cortisol (nM) (after a low dose DEX) Cortisol (nM) (after a high dose DEX) ACTH (PM) (after a high dose DEX) K+ (mm) Result 6.2 79 750 747 152 2.35 Reference Range 2.5-7.0 60-120 138-690 138 - 690 <26 3.5-5.0 Based on the patient presentation and the test results in the table, state what is the most probable diagnosis, and also the most common specific cause underlying this diagnosis. (20 words)
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