A 79 kg man is admitted to hospital following a suspected overdose of drug G. When he is admitted to hospital on the 3rd October at 23:00 his plasma concentration of drug G is 12 mg/mL. Given that the half-life (t½) of drug G is 10.5 hours. What would you expect his plasma concentration of drug G to be at 17:00 on the 5th October? Give the answer in microg/ml. (You may assume that the distribution is complete and the elimination is described by a 1storder

A child has been prescribed pethidine 35mg IM at 0800 hours. 1ml Stock ampoules have been labelled 5% pethidine. What volume must be drawn up for injection? ?????? ????????= ???????ℎ ????????/????? ???????ℎ x (volume of stock solution)

Calculate the following dosage: A doctor's prescription for pepcid is 15.5 mg per kg of body weight per dose. For an adult who weighs 135 lbs, calculate the number of grams to be given in a dose.

The antibiotic A is administered as a 1.0 g IV-bolus to a 34 years old male subject.  The following plasma concentration data were collected:     Time (hr) Concentrations (mg/L) 0.2 21.51 0.5 17.18 1 12.26 1.5 8.88 2 6.63 3 4.08 4 2.78 8 1.02 12 0.45 24 0.04   Calculate the following parameters (use Excel and the curve stripping method):   PARAMETER VALUE UNITS Elimination half-life (b)     Elimination half-life (k10)     Distribution rate constant     V1     Vss     Clearance     AUC

The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml.  If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?

A 77 kg patient is receiving the following "2-in-1" admixed TPN: Glucose 330 g Amino acids 143 g Total volume: 2310 mL What should the rate of infusion be, in mL/hr, if the TPN is run over 24 hours? Round to the nearest 5 mL/hr, do not enter units Answer:

2 mcg/kg/min Pt weighs 165 lbs. Drug 50mg in 1000mL. How many mL/hr.?

4) A 45-year old woman weighing 68 kg is admitted to hospital after a drug overdose. A toxic plasma concentration of 264 mg/mL is recorded on admission. After 35 hours, a plasma concentration of 8.25mg/ml is recorded. Given this information, calculate the half life for this drug.(Assume the distribution is complete and that the elimination is described by a first-order process.)unit- hours

A 24-year-old female has just delivered a baby and will receive 1.9 grams/hr of magnesium sulfate for eclampsia. How many mEq of magnesium sulfate (MW 120; valence 2) will the patient receive in 24 hours?

You are asked by the pharmacist to add 45 mEq of Ca Gluconate in an IV bag of D5W 1000mL. You have a concentrated vial of Ca Gluconate 4.4 mEq/mL, 50 mL. How many mL of this concentrated vial needs to be added to the IV bag?