A 62-year-old man is initially seen in the Emergency Room complaining of difficulty with speech and swallowing due to an enlarged tongue. Physical examination also reveals a large, sublingual hematoma. In addition, multiple ecchymoses of his skin are noted. He has no history of trauma nor has there been any pervious episodes of bleeding. Coagulation studies show: Platelet Count: 180,000/cumm PT: 12 sec APPT: 72 sec TCT or thrombin time: 10 sec Fibrinogen: 225% Additional laboratory studies reveal: (Mixing Studies) Normal plasma: 20% 50% 80% Patient plasma 80% 50% 20% Repeat APPT: 72 sec 70 sec 68 sec Question: What additional Laboratory test to confirm the diagnosis? Give the relevance of the laboratory tests ordered to the case. Why it is necessary? The additional test is von willebrand test because it's specific for clotting factor 8. Why is it necessary
A 62-year-old man is initially seen in the Emergency Room complaining of difficulty with speech and swallowing due to an enlarged tongue. Physical examination also reveals a large, sublingual hematoma. In addition, multiple ecchymoses of his skin are noted. He has no history of trauma nor has there been any pervious episodes of bleeding. Coagulation studies show:
Platelet Count: 180,000/cumm
PT: 12 sec
APPT: 72 sec
TCT or thrombin time: 10 sec
Fibrinogen: 225%
Additional laboratory studies reveal: (Mixing Studies)
Normal plasma: 20% 50% 80%
Patient plasma 80% 50% 20%
Repeat APPT: 72 sec 70 sec 68 sec
Question:
What additional Laboratory test to confirm the diagnosis? Give the relevance of the laboratory tests ordered to the case. Why it is necessary?
The additional test is von willebrand test because it's specific for clotting factor 8. Why is it necessary?
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