A 19-year-old male visits his primary care physician with a sore throat, swollen lymph nodes, and extreme fatigue. During the visit, the nurse finds that he has a fever. The patient reports that he is attending his second year of college at a local university. The physician performs a physical examination, which confirms large, swollen, painful lymph nodes. He decides to send the patient to the office laboratory for blood work. He orders a complete blood count (CBC) and viral and bacterial studies. Reference Range Reference Range WBC 13.3 × 103/uL 4.8–10.8 × 103/uL Neutrophils 40% 60%–70% RBC 4.5 × 109/L 4.7–6.1 × 109/L Lymphocytes 53% *20% of lymphocytes are atypical 20%–30% Hgb 14.1 g/dL 14–18 g/dL Monocytes 7% 5%–10% Hct 42% 42%–52% Eosinophils 0 0%–5% MCV 92 fL 80–100 fL Basophils 0 0%–2% MCH 27 pg 27–31 pg Absolute neutrophils 5.32 1.4–6.5 × 103/uL MCHC 33% 32% –36% Absolute lymphocytes 7.05 1.2–3.4 × 103/uL RDW 14.3% 11.5%–14.5% Absolute monocytes 0.93 0.1–0.6 × 103/uL Plt 325 × 109/L 150–450 × 109/L Absolute eosinophils 0 0–0.5 × 103/uL MPV 9.5 fL 7.4–10.4 fL Absolute basophils 0 0–0.2 × 103/uL Question: The patient’s symptoms of fever and painful, swollen lymph nodes are caused by what innate immune mechanisms? Explain your answer About 50% of patients with chronic viral infection develop splenomegaly. Based on what you know about the organs of the immune system, why would this condition develop? NOTE: please answer all questions. Thank you!

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

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A 19-year-old male visits his primary care physician with a sore throat, swollen lymph nodes, and extreme fatigue. During the visit, the nurse finds that he has a fever. The patient reports that he is attending his second year of college at a local university. The physician performs a physical examination, which confirms large, swollen, painful lymph nodes. He decides to send the patient to the office laboratory for blood work. He orders a complete blood count (CBC) and viral and bacterial studies.

		Reference Range			Reference Range
WBC	13.3 × 10³/uL	4.8–10.8 × 10³/uL	Neutrophils	40%	60%–70%
RBC	4.5 × 10⁹/L	4.7–6.1 × 10⁹/L	Lymphocytes	53% *20% of lymphocytes are atypical	20%–30%
Hgb	14.1 g/dL	14–18 g/dL	Monocytes	7%	5%–10%
Hct	42%	42%–52%	Eosinophils	0	0%–5%
MCV	92 fL	80–100 fL	Basophils	0	0%–2%
MCH	27 pg	27–31 pg	Absolute neutrophils	5.32	1.4–6.5 × 10³/uL
MCHC	33%	32% –36%	Absolute lymphocytes	7.05	1.2–3.4 × 10³/uL
RDW	14.3%	11.5%–14.5%	Absolute monocytes	0.93	0.1–0.6 × 10³/uL
Plt	325 × 10⁹/L	150–450 × 10⁹/L	Absolute eosinophils	0	0–0.5 × 10³/uL
MPV	9.5 fL	7.4–10.4 fL	Absolute basophils	0	0–0.2 × 10³/uL

Question:

The patient’s symptoms of fever and painful, swollen lymph nodes are caused by what innate immune mechanisms? Explain your answer
About 50% of patients with chronic viral infection develop splenomegaly. Based on what you know about the organs of the immune system, why would this condition develop?

NOTE: please answer all questions. Thank you!

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