8) The PLP-dependent enzyme 8-aminolevulonic acid synthase catalyzes the biosynthesis of aminolevulonic acid from glycine succinyl-CoA in the first step of heme biosynthesis. Propose reaction mechanism illustrating the role of PLP.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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8) The PLP-dependent enzyme ô-aminolevulonic acid synthase catalyzes the
biosynthesis of aminolevulonic acid from glycine succinyl-CoA in the first
step of heme biosynthesis. Propose reaction mechanism illustrating the role
of PLP.
9) Illustrate the role of PLP in the biosynthesis of the bioactive amines.
• Histamine
• Dopamine
Serotonin
Transcribed Image Text:8) The PLP-dependent enzyme ô-aminolevulonic acid synthase catalyzes the biosynthesis of aminolevulonic acid from glycine succinyl-CoA in the first step of heme biosynthesis. Propose reaction mechanism illustrating the role of PLP. 9) Illustrate the role of PLP in the biosynthesis of the bioactive amines. • Histamine • Dopamine Serotonin
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