7. Which of the following is true of water in the hydration layer of proteins? a. It has a lower AS than bulk water b. It has a higher AS than bulk water c. It has a lower AH than bulk water d. It has a higher AH than bulk water e. None of the above 8. An enzyme-catalyzed reaction rate will be increased if the energy level of ES can be increased. Which of the following will not increase the energy level of ES? a. destabilization of ES by solvation b. Destabilization of ES by strain caused by non-covalent interaction between E and S c. Loss of entropy due to binding of E and S d. Destabilization of ES by distortion e. Destabilization of ES by electrostatic effects 9. The catalytic mechanism below is an example of: Mechanism O H* CH,C-0 NO CH-Co CH,C-O + HO -NO, + H* HN, a. General base catalysis b. Specific acid catalysis c. Covalent electrophilic catalysis d. Covalent nucleophilic catalysis e. None of the above

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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7.
Which of the following is true of water in the hydration layer of proteins?
a. It has a lower AS than bulk water
b. It has a higher AS than bulk water
c. It has a lower AH than bulk water
d. It has a higher AH than bulk water
e. None of the above
8. An enzyme-catalyzed reaction rate will be increased if the energy level of ES can be
increased. Which of the following will not increase the energy level of ES?
a. destabilization of ES by solvation
b. Destabilization of ES by strain caused by non-covalent interaction between E and S
c. Loss of entropy due to binding of E and S
d. Destabilization of ES by distortion
e. Destabilization of ES by electrostatic effects
9. The catalytic mechanism below is an example of:
Mechanism
O H*
CH,C-0
NO,
CH,C-O + HO-
-NO, + H*
H-0
H.
HN,
a. General base catalysis
b. Specific acid catalysis
c. Covalent electrophilic catalysis
d. Covalent nucleophilic catalysis
e. None of the above
Transcribed Image Text:7. Which of the following is true of water in the hydration layer of proteins? a. It has a lower AS than bulk water b. It has a higher AS than bulk water c. It has a lower AH than bulk water d. It has a higher AH than bulk water e. None of the above 8. An enzyme-catalyzed reaction rate will be increased if the energy level of ES can be increased. Which of the following will not increase the energy level of ES? a. destabilization of ES by solvation b. Destabilization of ES by strain caused by non-covalent interaction between E and S c. Loss of entropy due to binding of E and S d. Destabilization of ES by distortion e. Destabilization of ES by electrostatic effects 9. The catalytic mechanism below is an example of: Mechanism O H* CH,C-0 NO, CH,C-O + HO- -NO, + H* H-0 H. HN, a. General base catalysis b. Specific acid catalysis c. Covalent electrophilic catalysis d. Covalent nucleophilic catalysis e. None of the above
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