6. Determine whether the following reactions are SN1 or SN2. Draw the mechanism and the products with stereochemistry. a. b. Br Br + "CN + -OCH3 acetone DMSO d. Br Y f. + CH3OH + CH,CO,H Br + OCH₂CH3 + CH₂CH₂OH DMF 1, 2 of 2

Identify the correct statement for the given reactions given. High Temp. NBS/ CH;Cl, + H-Br Reaction A Br V + Br-Br Br Room Temp. Br. CH;Cl, Reaction B O Reaction A needs a carbocation intermediate , and reaction B needs a radical intermediate Reaction A needs a radical intermediate , and reaction B needs a bridge carbocation intermediate O Reactions A and B both need radicals but they are different. O Both A and B needs carbocations but they are different

What is the major product of the following reaction? HBr, warm O a. (E)-1-bromobut-2-ene O b. 4-bromobut-1-ene O c. (Z)-2-bromobut-2-ene O d. none of the other answers O e. racemic 3-bromobut-1-ene

Question 6 Select the major product of the reaction sequence below. CI оо CHNH2 dočNH, 1. (COCI)2 -CO2H 2. NH3 3. SOCI2 оо CN -CNC D. O O OO

7. Predict the major product or provide the reagents in the following reactions. Be sure to show stereochemistry if necessary. ? CrO3, H2SO4, H20 a. Br HO. acetone b. 1. MgBr 2. H3O* workup с. NABH4 H. MeOH d. Br Mg, Et,0 MeOH

Using the reaction bank, devise a synthetic route (should use several reactions) to convert the starting material into the product. Remember, order is important. H;N HyN HO HO Structure 1 Structure 2 Reaction Bank: Reaction A HCHC Reaction B. DCCD, HCI Reaction C CF CO.H Step 1: Reaction A+ Structure 2

What is the predominant mechanism by which this reaction occurs? Select one: OA. E2 OB. Sn2 O C. E1 OD. Sn1 I list. THF L; Ⓒ

Can you show the mechanism and the products for those problems especially the ones that I put circle on

15. Draw the major product(s) of the following reactions. Write N.R. if there no reaction. H. 1) CH,MgBr 2) H,O 1) (CH)CuLi 2) HO H. (CH) NH (CH3)2NH CH,NH, of (CH3)N H. CH3OH (1 equiv.) H. H* CH,OH (excess) H* H2SO4 H. HCN Page 6

The last option is 5. C