5. The Friedel-Crafts alkylation reaction below does not give high yields of the desired product. Select two reasons why. A. The electrophile is too poor to react with benzene. B. The carbocation will rearrange. C. Chlorine will substitute, not the alkyl group. D. Polyalkylation occurs. E. The wrong catalyst was used. AICI, poor yield

Select all of the molecules that will readily undergo a 1,2-hydride or a 1,2-methyl shift to form a more stable carbocation.

Which is the correct nucleophile in the following reaction? A. CH3MgBr 1) ? 2) H₂O OH B. CH3CH₂CH₂MgBr C. CH3CH₂MgBr D. PhMgBr

24. Rank the following alkyl bromides in order from slowest to fastest in each type of mechanism. Briefly explain. Br a. SN2 b. SN1 c. E2 d. E1 Br Br

Which of the following is a correct statement regarding electrophilic aromatic substitution? A. Many suitable electrophiles are unreactive and can be stored for long periods of time prior to use. B. The carbocation intermediate will lose a proton to regain aromaticity, usually from a position other than the site of the electrophilic attack. C. Formation of the carbocation intermediate has a high activation barrier due to loss of aromaticity. D. Reformation of the aromatic ring has a low activation barrier and therefore occurs slowly. E. The carbocation intermediate has several resonance structures and is negatively charged.

Which of the following does not convert a primary alcohol into a good leaving group for an SN2 reaction? a. SOCI2/pyridine b. TSCI/pyridine c. PBr3 d. Nal a

Choose the right answer

Which  reacts the most rapidly in a nucleophilic substiution reaction?   a. 2-Iodo-2-methylpropane   b. 2-Chloro-2-methylpropane   c. 2-Bromo-2-methylpropane   d) They would all react at the same rate