4. Propose a synthesis of each of the following compounds, from the given starting material and any other needed reagents. (а) Br -NO2 from (b) O,N- =CH2 from -CH2-CH3

draw the products obtained in each of the following reactions.

Provide structure(s) for the starting material(s), reagent(s) or the major organic product(s) of each of the following reactions.

Describe a sequence of reactions by which hept-1-yne can be straightforwardly prepared from hept-1-ene.

3. For each of the following reactions, fill in the missing products, reactants, or reagents as appropriate. Account for stereochemistry when appropriate. CI Br KCN CH3OH Ph CH3OH (а) (b) CH3 CH3 KO'Bu 'BUOH Br

3) Complete the following chemical equations. Make sure to clearly indicate the stereochemistry in each product if applicable. а) HOʻ SOCI2, EtzN CH3SNA, CH3SH b) NaH HO H Cl CH3 HBr CH2CH3

МЕСНANISMS 1,2-epoxy-1-methylcyclopentane undergoes both acid-catalyzed and base-catalyzed opening of the epoxide ring to form two different products. > Using ethanol as the solvent and an appropriate acid, show the steps in the acid catalyzed mechanism, writing structures for all products of the steps. Circle the major product(s). > Using ethanol as the solvent and an appropriate base, show the steps in the base- catalyzed mechanism, writing structures for all products of the steps. Circle the major product(s). 1,2-epoxy-1-methylcyclopentane CH3

Give the major organic product(s) for cach of the following reactions or sequences of reactions. Show all relevant stereochemistry. CN 1.(CH) CHM Br, ether 2. HO

give the major products of this reaction. include stereochemistry as appropiate. strongly appreciate it.