4.) NH₂ (A) H 0₂ N H (B) H₂CO H H (D) OH

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4. Which molecule has the lowest pKa for the H proton at the very bottom (the H that's in the same spot for all the molecules)? Please explain your reasoning.

 

NH₂
(A)
H
0₂ N
H
(B)
H₂Co
(c)
H
H
(D)
OH
Transcribed Image Text:NH₂ (A) H 0₂ N H (B) H₂Co (c) H H (D) OH
Expert Solution
Step 1: concept

Based on the stability of conjugate base of compound, acidity vary. With increasing the stability of conjugate base, acidity increases. 

+R group increase the electron density on benzene ring that results decrease in acidity. 

-R group decrease the electron density on benzene ring that results increase in acidity. 

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