3. Determine if the pedigree below can be for a trait that is autosomal dominant. a. Write the genotype of each individual next to the symbol. FIG. A.3 b. Is it possible that this pedigree is for an autosomal dominant trait? c. In conclusion, can two individuals that have an autosomal dominant trait have unaffected children? 4. Assume that the pedigree below is for a recessive trait. Write the genotype next to the symbol for each person. FIG. A.4
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Pedigree chart
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- 36. Look at this pedigree and circle each row yes/no. Any assumption (that is not outrageous) can be made), for example, can assume someone is a carrier. a. Could this trait be inherited as a simple autosomal recessive? YES oo 8995 ON b. Could this trait be inherited as a simple autosomal dominant? YES ON C. Could this trait be inherited as a simple x linked recessive? YES ON d. Could this trait be inherited as a simple x linked dominant? YES ON e. Could this trait be inherited as a Y linked? YES ON3) A. How are the following proteins involved in cell division: condensing, cohesin, kinetochore complex, tubulin? B. Why does phenotype not always reveal genotype? C. How can Mendel's postulates of segregation and independent assortment be explained by meiosis? D. Explain the genotypic and phenotypic ratios predicted when performing a monohybrid and a dihybrid cross of heterozygotes? E. How can you use the product rule and sum rule to calculate the probability of a particular genotype resulting from crossing parents of specific genotypes?7. a. What is the most probable mode of inheritance for this trait? ܐܘܬܬ b. For each of the other 3 modes of inheritance, briefly explain why it is not possible (or not the most probable Give individuals in the pedigree as evidence (use the I-2 form for designating them).
- A. Identify the pattern of inheritance in the pedigree below. B. Provide two pieces of evidence that you used to come to this conclusion. C. Identify the genotypes of individuals II-1 and III-2 (at the arrows)What are the genotypes of the mother and father in the pedigree below? The pedigree shows albinism (an autosomal recessive trait). The shaded shapes represent albino individuals. a. mother - homozygous dominant; father - homozygous dominant b. mother - heterozygous; father - homozygous recessive c. mother - homozygous recessive; father - heterozygous d. mother - heterozygous; father - heterozygous e. mother - homozygous dominant; father - homozygous recessiveGeneration a. What is the genotype of the mother? b. What is the genotype of the father? c. What are the genotypes of the five children" 41. What is/are the possible inheritance pattern(s) for the characteristic in the following pedigree? 11 a. Autosomal recessive only i b. Autosomal dominant only) c. X-linked recessive only d. X-linked dominant only e. All of the above are possible. 42. What is/are the possible inheritance pattern(s) for the characteristic in the following pedigree? 11 a Autosomal recessive only b. Autosomal dominant only c. X-linked recessive only d X-linked dominant only e. All of them are possible. 43. If the phenotype followed in the pedigree below is X-linked recessive, then the genotype of 11-2 is HI a homozygous dominant b heterozygous chomozygous recessive d hemuzygous dominant e bemizygous recessive
- 9. We will determine if the pedigree below can be for a trait that is autosomal dominant. Use "A" and "a" where A represents the dominant allele and "a" is the recessive allele. Darken symbol means the individual exhibits the dominant trait.e a) Write the genotype of each individual next to the symbol.e b) Is it possible that this pedigree is for an autosomal dominant trait?e1. Which best describes the mode of inheritance of the afflicting allele in the following pedigree? A. autosomal dominant B. autosomal recessive C. X-linked dominant D. X-linked recessive 2. Suppose that an allele, b, of a X-linked gene is recessive and lethal (if a wild-type allele is not present). A man marries a woman who is heterozygous for this gene. If this couple had a large number of normal children, what would be the predicted sex ratio of these children (ratio of male children to female children)?O StompOnStep1.com a. Assume this pedigree represents inheritance of a human disease. What is the most likely mode of inheritance for this disease? b. What is the most likely genotype person III-IV if we use A and a as the alleles for this disease? a. Autosomal dominant, b. Aa a. Y linked, b. Aa a. Autosomal dominant, b. AA a. Autosomal recessive, b. aa
- 3) The most likely inheritance pattern in the pedigree above is:Two autosomal mutations include albinism and dwarfism. Albinism (a) is recessive, and dwarfism (D) is dominant. Complete a dihybrid cross of two people that are heterozygous for normal pigmented skin. One person is normal height and has no genetic trace of dwarfism in the family. The other person has dwarfism but has a mother who is normal height. 21. Complete a full dihybrid Punnett square (6pts).|| IV V Examine the pedigree and determine which of the following modes of inheritance best explains this trait: A. Autosomal dominant B. Autosomal recessive C. X-linked dominant D. X-linked recessive E. Y-linked F. Mitochrondrial A. Explain why the trait is best described by the mode of inheritance you conclude. B. Using your hypothesis, determine the genotypes of the pair in generation I and the members of generation V. Explain and justify your answers