Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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![Q20. Dr. Rose Lees is a world expert on breast cancer. Choose True or False.
Of all the receptors involved, the HER2+ has a worse
[ Choose ]
prognosis.
[ Choose ]
BRCA1 helps repair damaged DNA, or destroy cells if
DNA cannot be repaired.
True
False
The nuclear hormone receptors contain a DNA binding
domain towards the C-terminus.
[Choose]
The nuclear hormone receptors contain a ligand binding
domain toward the C-terminus.
[ Choose]
The main function of the estrogen receptor is as a DNA
binding transcription factor.
[ Choose ]
The last a-helix, helix 12, folds into a groove on the side
of the structure upon ligand binding.
[Choose ]
Upon binding of tamoxifen to the estrogen receptor, helix
12 exposes the coactivator-binding site.
[ Choose ]
>](https://content.bartleby.com/qna-images/question/86e70994-fd4f-4fd8-99fd-62e71dddaac3/5f804786-6787-4182-ba33-f0da0ecce23d/v267bc_processed.jpeg)
Transcribed Image Text:Q20. Dr. Rose Lees is a world expert on breast cancer. Choose True or False.
Of all the receptors involved, the HER2+ has a worse
[ Choose ]
prognosis.
[ Choose ]
BRCA1 helps repair damaged DNA, or destroy cells if
DNA cannot be repaired.
True
False
The nuclear hormone receptors contain a DNA binding
domain towards the C-terminus.
[Choose]
The nuclear hormone receptors contain a ligand binding
domain toward the C-terminus.
[ Choose]
The main function of the estrogen receptor is as a DNA
binding transcription factor.
[ Choose ]
The last a-helix, helix 12, folds into a groove on the side
of the structure upon ligand binding.
[Choose ]
Upon binding of tamoxifen to the estrogen receptor, helix
12 exposes the coactivator-binding site.
[ Choose ]
>
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