2. Using Avogadro to assist, please assign the absolute configuration all the chiral centers in the molecule amoxicillin. HO NH₂ NH₂ H HO

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2. Using Avogadro to assist, please assign the absolute configuration of all the chiral centers in the molecule amoxicillin.

#### Diagram Explanation:

The diagram is a structural representation of the amoxicillin molecule. Key features include:

- **Benzene ring**: On the left side, there’s a six-carbon ring with alternating double bonds, indicative of a benzene structure, with a hydroxyl group (OH) attached.
- **Lactam ring**: A four-membered cyclic amide is present, which is characteristic of the β-lactam antibiotic family.
- **Chiral centers**: The structure highlights multiple chiral centers, marked in the diagram by intersecting lines and, possibly, dashed or wedged bonds (not clearly visible here).
- **Functional groups**: Includes an amino group (NH₂) attached to the β-lactam ring portion, an additional amino group above the lactam ring, an oxo group (=O), and a carboxyl group (COOH) bonded to a nearby carbon.

The task requires identifying the configuration (R or S) of each chiral center using molecular visualization software like Avogadro.
Transcribed Image Text:2. Using Avogadro to assist, please assign the absolute configuration of all the chiral centers in the molecule amoxicillin. #### Diagram Explanation: The diagram is a structural representation of the amoxicillin molecule. Key features include: - **Benzene ring**: On the left side, there’s a six-carbon ring with alternating double bonds, indicative of a benzene structure, with a hydroxyl group (OH) attached. - **Lactam ring**: A four-membered cyclic amide is present, which is characteristic of the β-lactam antibiotic family. - **Chiral centers**: The structure highlights multiple chiral centers, marked in the diagram by intersecting lines and, possibly, dashed or wedged bonds (not clearly visible here). - **Functional groups**: Includes an amino group (NH₂) attached to the β-lactam ring portion, an additional amino group above the lactam ring, an oxo group (=O), and a carboxyl group (COOH) bonded to a nearby carbon. The task requires identifying the configuration (R or S) of each chiral center using molecular visualization software like Avogadro.
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