2. ( Of all the chromosomal disorders, abnormalities in chromosome number are the most easily identifiable from a karyotype (chromosome smear). While most of the time, meiosis occurs "correctly", occasionally pairs of homologous chromosomes fail to separate during meiosis. This is called nondisjunction. The risk of nondisjunction increases with the age of the parents. Nondisjunction can occur at meiosis I or meiosis II 1. For a diploid cell with n= two chromosomes (so the cell has 2n=4 chromosomes), draw pictures, label the stages, and explain the outcome if nondisjunction occurs at meiosis I or meiosis II. 2. In each case, indicate the percent of gametes that have the normal complement of chromosomes, one extra, and one too few. 3. Give an example of a disease or syndrome that is the result of nondisjunction. Indicate the chromosome involved.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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2.
Of all the chromosomal disorders, abnormalities in chromosome number are the most easily identifiable
from a karyotype (chromosome smear). While most of the time, meiosis occurs "correctly", occasionally pairs of
homologous chromosomes fail to separate during meiosis. This is called nondisjunction. The risk of nondisjunction
increases with the age of the parents. Nondisjunction can occur at meiosis I or meiosis II
1. For a diploid cell with n= two chromosomes (so the cell has 2n=4 chromosomes), draw pictures, label the stages,
and explain the outcome if nondisjunction occurs at meiosis I or meiosis II.
2. In each case, indicate the percent of gametes that have the normal complement of chromosomes, one extra, and
one too few.
3. Give an example of a disease or syndrome that is the result of nondisjunction. Indicate the chromosome
involved.
Transcribed Image Text:2. Of all the chromosomal disorders, abnormalities in chromosome number are the most easily identifiable from a karyotype (chromosome smear). While most of the time, meiosis occurs "correctly", occasionally pairs of homologous chromosomes fail to separate during meiosis. This is called nondisjunction. The risk of nondisjunction increases with the age of the parents. Nondisjunction can occur at meiosis I or meiosis II 1. For a diploid cell with n= two chromosomes (so the cell has 2n=4 chromosomes), draw pictures, label the stages, and explain the outcome if nondisjunction occurs at meiosis I or meiosis II. 2. In each case, indicate the percent of gametes that have the normal complement of chromosomes, one extra, and one too few. 3. Give an example of a disease or syndrome that is the result of nondisjunction. Indicate the chromosome involved.
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