14) Devise a synthesis of the following compound using 1-bromobutane as the only organic starting material.

Provide reagents

Ibufenac, a para-disubstituted arene with the structureHO2CCH2C6H4CH2CH(CH3)2 , is a much more potent analgesic thanaspirin, but it was never sold commercially because it caused livertoxicity in some clinical trials. Devise a synthesis of ibufenac frombenzene and organic halides having fewer than five carbons.

Propose a multi-step synthetic route to form the polycyclic molecule on the right hand side using the following reagents on the left hand side of the arrows: i) cyclic ketone; ii) a,ẞ-unsaturated ketone; iii) either the organocuprate OR the organolithium reagent listed; and ii) any other reagents or solvents of your choosing The depicted reagents represent all necessary building blocks that are directly incorporated into the molecule on the right, however you should use additional reagents to help facilitate its construction based on Chem 110 content from Chapters 21 and 23. This is a multi-step synthesis and not all reagents will be used at the same time. When describing your solution, show the stable intermediates along your proposed synthetic route and number the individual synthetic steps. You do not have to worry about stereochemistry in this particular question. For two (2) of your proposed steps, show individual mechanistic arrows that show the flow of electrons during that…

Hi, it's just one question but 3 subparts, and you are only allowed to answer up to 3 sub-parts please show the work clearly for all. Thank You

Provide the structure of the two organic product(s) which results when 2-bromo-2-methylbutane is treated with sodium ethoxide.

a) Suggest a synthesis of the compound shown below. You are required to first do a retrosynthesis leading to commercially available starting material, and then the corresponding synthesis. In your synthesis, you may use any inorganic reagents you think I will assist in your synthesis, but can only use the following organic reagents; saturated hydrocarbon chain with 5 or less carbons and one functional group, unsaturated hydrocarbon chain with 5 or less carbons and one functional group in addition to the alkene or alkyne, saturated hydrocarbon ring with 6 or less carbons and one functional group, and unsaturated hydrocarbon ring with 6 or less carbons and one functional group. за

To obtain 2,4,4-trimethyl-2-pentanal, write down the reaction mechanism using 2,2-dimethylpropanal and other necessary reagents.

a) b) 1. Provide the necessary reagents to carry out the following transformations. 왜 H H OMe