12. (a) Using Eq. AQ=CAV and the data in the Table, calculate the number of ions entering the axon during the action potential, per meter of nonmyelinated axon length. (The charge on the ion is 1.6 x 10-19 Coulomb.) (b) During the resting state of the axon, typical concentrations of sodium and potassium ions inside the axon are 15 and 150 millimole/liter, respectively. From the data in the Table, calculate the number of ions per meter length of the axon. Axonc

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12. (a) Using Eq. AQ=CAV and the data in the Table, calculate the number of ions entering the axon during
the action potential, per meter of nonmyelinated axon length. (The charge on the ion is 1.6 x 10-19 coulomb.)
(b) During the resting state of the axon, typical concentrations of sodium and potassium ions inside the axon
are 15 and 150 millimole/liter, respectively. From the data in the Table, calculate the number of ions per
meter length of the axon.
Table 13.1 Properties of Sample Axons
Hint:
1 F (farad) = 1coulomb/1 volt
Property
Nonmyelinated axon
Myelinated axon
Axon radius
5 x 10-m
5 x 10-6 m
1 mole /liter = 6.02 x 1020 particles (ions, atoms, etc. ) Resistance per unit length of fluid
cm
6.37 x 10°2/m
6.37 x 10°2/m
both inside and outside axon (r)
Conductivity per unit length of
axon membrane (gm)
1.25 x 10-4 mho/m
In the resting state, the axon voltage is -70mV.
During the pulse, the voltage changes to about
+30mV, resulting in a net voltage change across
the membrane of 100 mV. Therefore, V to be used
in the equation AQ=CAV is 100 mV.
3 x 10-7 mho/m
Capacitance per unit length of
3 x 10-7 F/m
8 x 10-10 F/m
axon (c)
Transcribed Image Text:12. (a) Using Eq. AQ=CAV and the data in the Table, calculate the number of ions entering the axon during the action potential, per meter of nonmyelinated axon length. (The charge on the ion is 1.6 x 10-19 coulomb.) (b) During the resting state of the axon, typical concentrations of sodium and potassium ions inside the axon are 15 and 150 millimole/liter, respectively. From the data in the Table, calculate the number of ions per meter length of the axon. Table 13.1 Properties of Sample Axons Hint: 1 F (farad) = 1coulomb/1 volt Property Nonmyelinated axon Myelinated axon Axon radius 5 x 10-m 5 x 10-6 m 1 mole /liter = 6.02 x 1020 particles (ions, atoms, etc. ) Resistance per unit length of fluid cm 6.37 x 10°2/m 6.37 x 10°2/m both inside and outside axon (r) Conductivity per unit length of axon membrane (gm) 1.25 x 10-4 mho/m In the resting state, the axon voltage is -70mV. During the pulse, the voltage changes to about +30mV, resulting in a net voltage change across the membrane of 100 mV. Therefore, V to be used in the equation AQ=CAV is 100 mV. 3 x 10-7 mho/m Capacitance per unit length of 3 x 10-7 F/m 8 x 10-10 F/m axon (c)
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