Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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**Date:** November 6th, 2020

**Exercise:** 

**1. Rank the following substrates in order from slowest E1 reaction rate to fastest (slowest = 1, fastest = 4)**

**Substrates:**

- **Leftmost Structure:** Cyclohexane ring with a 2-bromo-2-methylpropane substituent.
  
- **Second Structure:** Cyclohexane ring with a 2-bromobutane substituent.
  
- **Third Structure:** Benzene ring with a 1-bromo-1-methylpropane substituent.
  
- **Rightmost Structure:** Benzene ring with a 1-bromo-2-methylpropane substituent. 

**Explanation:** 

The substrates differ in their molecular structures which determine the E1 reaction rate. An E1 reaction typically involves the formation of a stable carbocation intermediate. Stability is generally increased by factors such as resonance and hyperconjugation in the intermediate structures.

**Note:** 

Carefully analyze the carbocation stability for each substrate to accurately rank their respective E1 reaction rates.
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Transcribed Image Text:**Date:** November 6th, 2020 **Exercise:** **1. Rank the following substrates in order from slowest E1 reaction rate to fastest (slowest = 1, fastest = 4)** **Substrates:** - **Leftmost Structure:** Cyclohexane ring with a 2-bromo-2-methylpropane substituent. - **Second Structure:** Cyclohexane ring with a 2-bromobutane substituent. - **Third Structure:** Benzene ring with a 1-bromo-1-methylpropane substituent. - **Rightmost Structure:** Benzene ring with a 1-bromo-2-methylpropane substituent. **Explanation:** The substrates differ in their molecular structures which determine the E1 reaction rate. An E1 reaction typically involves the formation of a stable carbocation intermediate. Stability is generally increased by factors such as resonance and hyperconjugation in the intermediate structures. **Note:** Carefully analyze the carbocation stability for each substrate to accurately rank their respective E1 reaction rates.
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