Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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The image presents a chemical reaction involving a benzyl aldehyde derivative. Here's a detailed transcription and explanation:

**Chemical Structure:**
- The structure depicted at the top is a benzyl aldehyde, featuring a benzene ring attached to a chain ending with an aldehyde group (–CHO).

**Reaction Process:**
- The reaction involves three steps:
  1. **LDA**: Lithium diisopropylamide (LDA) is used as a strong, non-nucleophilic base to deprotonate the compound, generating an enolate ion.
  2. **CH₃CH₂CH₂CHO**: This is butyraldehyde, a three-carbon aldehyde introduced into the reaction. The enolate ion from the first step can add to this aldehyde in a nucleophilic addition reaction.
  3. **Neutralizing Work-up**: The final step involves neutralizing the reaction mixture, often done using an acid or base, to obtain the final product.

This sequence represents a typical aldol reaction, facilitating carbon-carbon bond formation between the starting material and the added aldehyde to extend the carbon chain.
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Transcribed Image Text:The image presents a chemical reaction involving a benzyl aldehyde derivative. Here's a detailed transcription and explanation: **Chemical Structure:** - The structure depicted at the top is a benzyl aldehyde, featuring a benzene ring attached to a chain ending with an aldehyde group (–CHO). **Reaction Process:** - The reaction involves three steps: 1. **LDA**: Lithium diisopropylamide (LDA) is used as a strong, non-nucleophilic base to deprotonate the compound, generating an enolate ion. 2. **CH₃CH₂CH₂CHO**: This is butyraldehyde, a three-carbon aldehyde introduced into the reaction. The enolate ion from the first step can add to this aldehyde in a nucleophilic addition reaction. 3. **Neutralizing Work-up**: The final step involves neutralizing the reaction mixture, often done using an acid or base, to obtain the final product. This sequence represents a typical aldol reaction, facilitating carbon-carbon bond formation between the starting material and the added aldehyde to extend the carbon chain.
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